{"id":101,"date":"2022-02-15T15:05:42","date_gmt":"2022-02-15T06:05:42","guid":{"rendered":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/_manage\/?page_id=101"},"modified":"2025-07-08T18:26:04","modified_gmt":"2025-07-08T09:26:04","slug":"cell-biochem","status":"publish","type":"page","link":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/education\/labo\/cell-biochem\/","title":{"rendered":"\u7d30\u80de\u751f\u5316\u5b66\u6559\u5ba4"},"content":{"rendered":"<section class=\"BlkAnchorArea\"><div class=\"BlkAnchorArea__inner\"><ul class=\"anchorMenu\"><li><a class=\"p-anchor\" href=\"#teacher\"><span>\u6559\u54e1<\/span><\/a><\/li><li><a class=\"p-anchor\" href=\"#summary\"><span>\u6982\u8981<\/span><\/a><\/li><li><a class=\"p-anchor\" href=\"#study\"><span>\u7814\u7a76<\/span><\/a><\/li><li><a class=\"p-anchor\" href=\"#achieve\"><span>\u696d\u7e3e<\/span><\/a><\/li><\/ul><\/div><\/section>\r\n<section class=\"BlkArticle__Contents--notLead\">\r\n  <div class=\"BlkArticle__btnlink--multi\">\r\n    <div class=\"BlkArticle__btnlink\">\r\n      <p><a class=\"u-icon_blank\" href=\"https:\/\/www.kyorin-u.ac.jp\/univ\/user\/medicine\/insulin\/\" target=\"_blank\" rel=\"noopener\"><span>\u6559\u5ba4\u30db\u30fc\u30e0\u30da\u30fc\u30b8<\/span><\/a><\/p>\r\n    <\/div>\r\n  <\/div>\r\n<\/section>\r\n<a id=\"teacher\" name=\"teacher\"><\/a>\r\n<section class=\"BlkArticle__Contents BlkArticle__Contents--notLead\">\r\n  <h2>\u6559\u5ba4\u5c02\u4efb\u6559\u54e1<\/h2>\r\n  \n<!-- staffdb 2023.08.15 -->\n<div><table class=\"BlkArticle__tableNormal BlkArticle__tableNormal--topLeft\" width=\"100%\" data-update=\"2023.08.15\"><tbody><tr><th>\u6559\u6388<\/th><td><ul class=\"list-on-td\"><li data-sort=\"0\uff0f72001\"><a href=\"\/univ\/faculty\/medicine\/education\/staffnew\/detail\/?id=med72001\" class=\"arrow\">\u9234\u6728\u3000\u7d62\u5b50<\/a><\/li><\/ul><\/td><\/tr><tr><th>\u52a9\u6559<\/th><td><ul class=\"list-on-td\"><li data-sort=\"0\uff0f72002\"><a href=\"\/univ\/faculty\/medicine\/education\/staffnew\/detail\/?id=med72002\" class=\"arrow\">\u82b3\u8cc0\u3000\u6cf0\u5f66<\/a><\/li><\/ul><\/td><\/tr><tr><th>\u52a9\u6559\uff08\u7279\u4efb\uff09<\/th><td><ul class=\"list-on-td\"><li data-sort=\"0\uff0f72003\"><a href=\"\/univ\/faculty\/medicine\/education\/staffnew\/detail\/?id=med72003\" class=\"arrow\">\u8352\u5185\u3000\u8cb4\u5b50<\/a><\/li><\/ul><\/td><\/tr><\/tbody><\/table><\/div> <\/section>\r\n<a id=\"summary\" name=\"summary\"><\/a>\r\n<section class=\"BlkArticle__Contents BlkArticle__Contents--notLead\">\r\n  <h2>\u6559\u5ba4\u6982\u8981<\/h2>\r\n  <p>\u7d30\u80de\u751f\u5316\u5b66\u6559\u5ba4\u304c\u62c5\u5f53\u3059\u308b\u5206\u5b50\u751f\u7269\u5b66\u3001\u7d30\u80de\u751f\u7269\u5b66\u306f\u3001\u533b\u5b66\u30fb\u533b\u7642\u306e\u5168\u5206\u91ce\u306b\u6e21\u3063\u3066\u6280\u8853\u7684\u30fb\u6982\u5ff5\u7684\u306b\u305d\u308c\u3089\u306e\u652f\u67f1\u3068\u306a\u3063\u3066\u3044\u308b\u5b66\u554f\u3067\u3042\u308a\u3001\u8fd1\u5e74\u306e\u7d44\u307f\u63db\u3048DNA\u9769\u547d\u3092\u7d4c\u3066\u7206\u767a\u7684\u306a\u767a\u5c55\u3092\u9042\u3052\u3066\u3044\u307e\u3059\u3002\uff11\u5e74\u751f\u3067\u306f\u5206\u5b50\u751f\u7269\u5b66\u3068\u907a\u4f1d\u5b50\u5de5\u5b66\u306e\u5b9f\u7fd2\u3092\u3001\uff12\u5e74\u751f\u3067\u306f\u7d30\u80de\u751f\u7269\u5b66\u306e\u30a8\u30c3\u30bb\u30f3\u30b9\u3092\u7fd2\u5f97\u3057\u3066\u3082\u3089\u3044\u307e\u3059\u3002\u4e00\u65b9\u3001\u7814\u7a76\u9762\u306b\u304a\u3044\u3066\u306f\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u958b\u53e3\u653e\u51fa\u306e\u5206\u5b50\u6a5f\u69cb\u3092\u89e3\u660e\u3059\u3079\u304f\u3001\u65e5\u591c\u5b9f\u9a13\u3092\u91cd\u306d\u3066\u3044\u307e\u3059\u3002\u3059\u306a\u308f\u3061\u3001\u907a\u4f1d\u5b50\u5de5\u5b66\u6280\u8853\u3001\u7d30\u80de\u751f\u7269\u5b66\u6280\u8853\u3001\u9855\u5fae\u93e1\u6280\u8853\u3092\u878d\u5408\u3055\u305b\u3066\u958b\u767a\u3057\u305f\u72ec\u81ea\u306e\u6280\u6cd5\u3092\u99c6\u4f7f\u3057\u3001\u81b5\u03b2\u7d30\u80de\u304b\u3089\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u653e\u51fa\u306e\u53ef\u8996\u5316\u306b\u4e16\u754c\u306b\u5148\u99c6\u3051\u3066\u6210\u529f\u3057\u3001\u6211\u304c\u56fd\u3067\u793e\u4f1a\u554f\u984c\u3068\u306a\u3063\u3066\u3044\u308b\u7cd6\u5c3f\u75c5\u6210\u56e0\u306e\u89e3\u660e\u306b\u7cbe\u529b\u7684\u306b\u53d6\u308a\u7d44\u3093\u3067\u3044\u307e\u3059\u3002<\/p>\r\n<\/section>\r\n<section class=\"BlkArticle__Contents BlkArticle__Contents--notLead\">\r\n  <h2>\u6559\u80b2\u306e\u7279\u8272<\/h2>\r\n  <p>\u30d2\u30c8\u30b2\u30ce\u30e0\u89e3\u6790\u304c\u307b\u307c\u5b8c\u4e86\u3057\u305f\u73fe\u5728\u3001\u5206\u5b50\u751f\u7269\u5b66\u306f\u3001\u533b\u5b66\u30fb\u533b\u7642\u306e\u3059\u3079\u3066\u306e\u5206\u91ce\u306b\u308f\u305f\u3063\u3066\u6280\u8853\u7684\u306b\u3082\u6982\u5ff5\u7684\u306b\u3082\u305d\u308c\u3089\u3092\u652f\u3048\u308b\u67f1\u3068\u306a\u3063\u3066\u304d\u3066\u3044\u308b\u3002\u81e8\u5e8a\u533b\u3068\u3044\u3048\u3069\u3082\u3001\u4eca\u3084\u5206\u5b50\u751f\u7269\u5b66\u306e\u7d20\u990a\u306a\u304f\u3057\u3066\u3001\u6025\u901f\u306a\u30b9\u30d4\u30fc\u30c9\u3067\u9032\u5316\u3057\u3066\u3044\u304f\u533b\u7642\u306b\u3064\u3044\u3066\u884c\u304f\u3053\u3068\u306f\u3067\u304d\u306a\u3044\u3002\u5f93\u3063\u3066M1\u3067\u306f\u3001\u5b66\u751f\u304c\u5c06\u6765\u81e8\u5e8a\u533b\u3068\u306a\u3063\u305f\u3068\u304d\u306b\u8981\u6c42\u3055\u308c\u308b\u5206\u5b50\u751f\u7269\u5b66\u304a\u3088\u3073\u907a\u4f1d\u5b50\u5de5\u5b66\u6280\u8853\u306b\u95a2\u3059\u308b\u6700\u4f4e\u9650\u306e\u77e5\u8b58\u3068\u8ad6\u7406\u3092\u4f53\u5f97\u3059\u308b\u3053\u3068\u3092\u76ee\u6a19\u3068\u3057\u3066\u3044\u308b\u3002<\/p>\r\n  <p>M2\u3067\u306f\u7d30\u80de\u30ec\u30d9\u30eb\u3067\u500b\u3005\u306e\u751f\u5316\u5b66\u7684\u4e8b\u8c61\u3092\u7d71\u5408\u7684\u306b\u628a\u63e1\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u75be\u60a3\u306e\u75c5\u614b\u751f\u7406\u306e\u7406\u89e3\u3092\u6df1\u3081\u308b\u3002M1\u3067\u7fd2\u5f97\u3057\u305f\u751f\u7269\u5b66\u3001\u5206\u5b50\u751f\u7269\u5b66\u3001\u751f\u5316\u5b66\u306e\u57fa\u790e\u77e5\u8b58\u3092\u3082\u3068\u306b\u3001\u500b\u3005\u306e\u751f\u5316\u5b66\u7684\u4e8b\u8c61\u3092\u7d30\u80de\u30ec\u30d9\u30eb\u3067\u306e\u7d71\u5408\u7684\u306a\u7406\u89e3\u3078\u3068\u767a\u5c55\u3055\u305b\u308b\u3002\u3053\u306e\u4f5c\u696d\u306b\u3088\u3063\u3066\u3001\u533b\u5e2b\u3092\u76ee\u6307\u3059\u5b66\u751f\u304c\u75be\u60a3\u306e\u75c5\u614b\u751f\u7406\u3092\u7406\u89e3\u3059\u308b\u305f\u3081\u306b\u5fc5\u8981\u306a\u7d30\u80de\u306e\u69cb\u9020\u30fb\u6a5f\u80fd\u3092\u5206\u5b50\u30ec\u30d9\u30eb\u304b\u3089\u7406\u89e3\u3059\u308b\u3053\u3068\u3092\u76ee\u6a19\u3068\u3057\u3066\u3044\u308b\u3002<\/p>\r\n<\/section>\r\n<section class=\"BlkArticle__Contents BlkArticle__Contents--notLead\">\r\n  <h2>\u793e\u4f1a\u7684\u6d3b\u52d5<\/h2>\r\n  <p>\u6559\u5ba4\u54e1\u306f\u4ee5\u4e0b\u306e\u5b66\u4f1a\u3067\u6d3b\u52d5\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\r\n  <p>\u65e5\u672c\u751f\u5316\u5b66\u4f1a<br>\r\n    \u65e5\u672c\u7cd6\u5c3f\u75c5\u5b66\u4f1a<br>\r\n    \u65e5\u672c\u795e\u7d4c\u79d1\u5b66\u4f1a<br>\r\n    \u65e5\u672c\u5185\u5206\u6ccc\u5b66\u4f1a<br>\r\n    \u65e5\u672c\u7d30\u80de\u751f\u7269\u5b66\u4f1a<\/p>\r\n<\/section>\r\n<a id=\"study\" name=\"study\"><\/a>\r\n<section class=\"BlkArticle__Contents BlkArticle__Contents--notLead\">\r\n  <h2>\u5927\u5b66\u9662\u6559\u80b2\u306e\u7279\u8272<\/h2>\r\n  <p>\u7d30\u80de\u751f\u5316\u5b66\u7814\u7a76\u3092\u901a\u3058\u3066\u79d1\u5b66\u7684\u601d\u8003\u3092\u8ad6\u7406\u7684\u306b\u5c55\u958b\u3059\u308b\u624b\u6cd5\u3092\u5b66\u3073\u3001\u79d1\u5b66\u8005\u3068\u3057\u3066\u57fa\u790e\u533b\u5b66\u306e\u89b3\u70b9\u306e\u307f\u306a\u3089\u305a\u81e8\u5e8a\u533b\u5b66\u306e\u4e21\u9762\u304b\u3089\u691c\u8a0e\u3092\u52a0\u3048\u7d30\u80de\u5206\u5b50\u30ec\u30d9\u30eb\u3067\u306e\u89e3\u660e\u3092\u76ee\u6307\u3059\u4eba\u6750\u306e\u80b2\u6210\u3092\u6559\u80b2\u306e\u57fa\u672c\u65b9\u91dd\u3068\u3057\u3066\u3044\u308b\u3002<\/p>\r\n<\/section>\r\n<section class=\"BlkArticle__Contents BlkArticle__Contents--notLead\">\r\n  <h2>\u7814\u7a76\u30c6\u30fc\u30de<\/h2>\r\n  <p>\u7d30\u80de\u751f\u5316\u5b66\u6559\u5ba4\u306e\u4e3b\u8981\u7814\u7a76\u30c6\u30fc\u30de\u306f\u3001\u81b5\u03b2\u7d30\u80de\u306b\u304a\u3051\u308b\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u306e\u5206\u5b50\u6a5f\u69cb\u306e\u89e3\u660e\u3067\u3042\u308b\u3002\u4eca\u3084\u65e5\u672c\u56fd\u6c11\u306e\u5065\u5eb7\u306b\u3068\u3063\u3066\u6700\u5927\u306e\u8105\u5a01\u3068\u306a\u3063\u3066\u3044\u308b\u7cd6\u5c3f\u75c5\u306e\u6210\u56e0\u89e3\u660e\u3001\u65b0\u305f\u306a\u4e88\u9632\u6cd5\u3001\u53ca\u3073\u65b0\u898f\u6cbb\u7642\u85ac\u306e\u958b\u767a\u306e\u305f\u3081\u306b\u306f\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u6a5f\u69cb\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u3053\u3068\u304c\u5206\u5b50\u7d30\u80de\u751f\u7269\u5b66\u306e\u89b3\u70b9\u304b\u3089\u306e\u307f\u306a\u3089\u305a\u3001\u81e8\u5e8a\u533b\u306b\u3068\u3063\u3066\u3082\u6025\u52d9\u306e\u8ab2\u984c\u3068\u306a\u3063\u3066\u3044\u308b\u3002\u65e5\u672c\u4eba\u306e\u7cd6\u5c3f\u75c5\u60a3\u8005\u6570\u306f\u4e88\u5099\u8ecd\u3092\u542b\u3081\u3066\u7d042,000\u4e07\u4eba\u3001\u304b\u3064\u3001\u6b7b\u4ea1\u7387\u9806\u4f4d2\uff0c3\u4f4d\u3092\u5360\u3081\u308b\u5fc3\u30fb\u8133\u8840\u7ba1\u969c\u5bb3\u306e\u767a\u75c7\u7387\u306f\u3001\u7cd6\u5c3f\u75c5\u7f79\u60a3\u8005\u306b\u304a\u3044\u3066\u975e\u7f79\u60a3\u8005\u306e3\u500d\u306b\u3082\u6607\u3063\u3066\u3044\u308b\u3002\u7279\u306b\u65e5\u672c\u4eba\u306e\u7cd6\u5c3f\u75c5\u306e\u7279\u5fb4\u306f\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u4e0d\u5168\u3092\u7279\u5fb4\u3068\u3057\u3066\u3044\u308b\u305f\u3081\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u6a5f\u69cb\u3092\u5206\u5b50\u30ec\u30d9\u30eb\u304b\u3089\u660e\u3089\u304b\u306b\u3059\u308b\u3053\u3068\u304c\u5f85\u3061\u671b\u307e\u308c\u3066\u3044\u308b\u3002\u305d\u3053\u3067\u3001\u5f53\u90e8\u9580\u306f\u65b0\u3057\u3044\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u624b\u6cd5\u3092\u7528\u3044\u3066\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u306e\u5206\u5b50\u6a5f\u69cb\u3092\u89e3\u660e\u3059\u308b\u3053\u3068\u306b\u7cbe\u529b\u7684\u306b\u53d6\u308a\u7d44\u3093\u3067\u3044\u308b\u3002\u30a4\u30f3\u30b9\u30ea\u30f3\u306f\u81b5\u03b2\u7d30\u80de\u5185\u306b\u3042\u308b\u30a4\u30f3\u30b9\u30ea\u30f3\u9846\u7c92\u3068\u5f62\u8cea\u819c\u304c\u878d\u5408\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u7d30\u80de\u306e\u5916\u306b\u653e\u51fa\u3055\u308c\u308b\u3002\u3053\u306e\u69d8\u306a\u30a4\u30f3\u30b9\u30ea\u30f3\u958b\u53e3\u653e\u51fa\u306e\u5206\u5b50\u6a5f\u69cb\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u305f\u3081\u306b\u306f\u3001\u751f\u304d\u305f\u7d30\u80de\u3092\u7528\u3044\u3066\u3001\u5358\u4e00\u30a4\u30f3\u30b9\u30ea\u30f3\u9846\u7c92\u306e\u52d5\u614b\u3092\u3001\u6642\u9593\u7684\u7a7a\u9593\u7684\u306b\u89e3\u6790\u3059\u308b\u3053\u3068\u304c\u5fc5\u9808\u3067\u3042\u308b\u3002\u305d\u3053\u3067\u3001\u5f53\u90e8\u9580\u306b\u304a\u3044\u3066\u306f\u3001\uff11\u5206\u5b50\u306e\u86cb\u767d\u8cea\u3092\u6349\u3048\u308b\u3053\u3068\u304c\u53ef\u80fd\u306atotal internal reflection fluorescence microscopy (TIRF)\u30b7\u30b9\u30c6\u30e0\u3092\u81b5\u03b2\u7d30\u80de\u306b\u69cb\u7bc9\u3057\u3001\u5358\u4e00\u30a4\u30f3\u30b9\u30ea\u30f3\u9846\u7c92\u3092\u30ca\u30ce\u30b9\u30b1\u30fc\u30eb\u306e\u7bc4\u56f2\u3001\u304b\u306433ms\u306e\u30d3\u30c7\u30aa\u30ec\u30fc\u30c8\u3067\u89e3\u6790\u3059\u308b\u30b7\u30b9\u30c6\u30e0\u3092\u78ba\u7acb\u3057\u305f\u3002\u3053\u306e\u30b7\u30b9\u30c6\u30e0\u3068\u3001\u5f93\u6765\u306e\u907a\u4f1d\u5b50\u5de5\u5b66\u7684\u624b\u6cd5\u306b\u3088\u308b\u907a\u4f1d\u5b50\u6539\u5909\u52d5\u7269\u3084\u7a2e\u3005\u306e\u30d7\u30ed\u30fc\u30d6\u3092\u7528\u3044\u305f\u5b9f\u9a13\u3092\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u306b\u3088\u308a\u3001\uff12\u76f8\u6027\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u306e\u4ed5\u7d44\u307f\u304c\u5f90\u3005\u306b\u660e\u3089\u304b\u306b\u306a\u308a\u3064\u3064\u3042\u308b\u3002<\/p>\r\n  <p>\u73fe\u5728\u3001\u7cd6\u5c3f\u75c5\u306b\u304a\u3051\u308b\u30a4\u30f3\u30b9\u30ea\u30f3\u958b\u53e3\u653e\u51fa\u306e\u7570\u5e38\u90e8\u4f4d\u3001\u65b0\u898f\u7cd6\u5c3f\u75c5\u85ac\u306e\u81b5\u03b2\u7d30\u80de\u306b\u304a\u3051\u308b\u4f5c\u7528\u7b49\u3092\u660e\u3089\u304b\u306b\u3057\u3066\u3044\u308b\u3068\u3053\u308d\u3067\u3042\u308b\u3002<\/p>\r\n  <p class=\"BlkArticle__txtlink\"><a href=\"https:\/\/www.kyorin-u.ac.jp\/univ\/user\/medicine\/insulin\/\" target=\"_blank\" class=\"u-icon_blank u-mgt_40\" rel=\"noopener\">\u7814\u7a76\u5185\u5bb9\u306e\u8a73\u7d30\u306f\u3001\u6559\u5ba4\u30db\u30fc\u30e0\u30da\u30fc\u30b8\u3078\u3002<\/a><\/p>\r\n<\/section>\r\n<a id=\"achieve\" name=\"achieve\"><\/a>\r\n<section class=\"BlkArticle__Contents BlkArticle__Contents--notLead\">\r\n  <h2>\u8fd1\u5e74\u306e\u4e3b\u306a\u696d\u7e3e<\/h2>\r\n  <ol class=\"BlkArticle__listNumber\">\r\n    <li>Aoyagi K, Nishiwaki C, Nakamichi Y, Yamashita SI, Kanki T, Ohara-Imaizumi M. (2024) Imeglimin mitigates the accumulation of dysfunctional mitochondria to restore insulin secretion and suppress apoptosis of pancreatic \u03b2-cells from db\/db mice. Sci Rep. 14(1):6178<\/li>\r\n    <li>Aoyagi K, Yamashita SI, Akimoto Y, Nishiwaki C, Nakamichi Y, Udagawa H, Abe M, Sakimura K, Kanki T, Ohara-Imaizumi M. (2023) A new beta cell-specific mitophagy reporter mouse shows that metabolic stress leads to accumulation of dysfunctional mitochondria despite increased mitophagy. Diabetologia 66: 147-162<\/li>\r\n    <li>Ohara-Imaizumi M, Aoyagi K, Ohtsuka T. (2019) Role of the active zone protein, ELKS, in insulin secretion from pancreatic b-cells. Mol Metab. 27: S81-S91<\/li>\r\n    <li>Ohara-Imaizumi M, Aoyagi K, Yamauchi H, Yoshida M, Mori MX, Hida Y, Tran HN, Ohkura M, Abe M, Akimoto Y, Nakamichi Y, Nishiwaki C, Kawakami H, Hara K, Sakimura K, Nagamatsu S, Mori Y, Nakai J, Kakei M, Ohtsuka T.(2019) ELKS\/Voltage-Dependent Ca2+ Channel-\u03b2 Subunit Module Regulates Polarized Ca2+ Influx in Pancreatic \u03b2 Cells. Cell Rep. 26(5):1213-1226<\/li>\r\n    <li>Aoyagi K, Itakura M, Fukutomi T, Nishiwaki C, Nakamichi Y, Torii S, Makiyama T, Harada A, Ohara-Imaizumi M.(2018) VAMP7 Regulates Autophagosome Formation by Supporting Atg9a Functions in Pancreatic \u03b2-Cells From Male Mice. Endocrinology. 159(11):3674-3688<\/li>\r\n    <li>Kunii M, Ohara-Imaizumi M, Takahashi N, Kobayashi M, Kawakami R, Kondoh Y, Shimizu T, Simizu S, Lin B, Nunomura K, Aoyagi K, Ohno M, Ohmuraya M, Sato T, Yoshimura SI, Sato K, Harada R, Kim YJ, Osada H, Nemoto T, Kasai H, Kitamura T, Nagamatsu S, Harada A. (2016) Opposing roles for SNAP23 in secretion in exocrine and endocrine pancreatic cells. J Cell Biol, vol.215: 121-138,<\/li>\r\n  <\/ol>\r\n  <h3>\u65e5\u672c\u8a9e\u306e\u89e3\u8aac\u30fb\u66f8\u7c4d\u306a\u3069<\/h3>\r\n  <ol class=\"BlkArticle__listNumber\">\r\n    <li>\u4eca\u6cc9\u7f8e\u4f73 (2025) \u30002\u76f8\u6027\u30a4\u30f3\u30b9\u30ea\u30f3\u958b\u53e3\u653e\u51fa\u306e\u5206\u5b50\u6a5f\u69cb \u65e5\u672c\u81e8\u5e8a, 83 \u5897\u520a:96-101<\/li>\r\n    <li>\u4eca\u6cc9\u7f8e\u4f73\u3001\u9752\u67f3\u5171\u592a (2024) \u30002\u76f8\u6027\u30a4\u30f3\u30b9\u30ea\u30f3\u958b\u53e3\u5206\u6ccc\u306e\u30e1\u30ab\u30cb\u30ba\u30e0 Diabetes Journal, 51:44-52<\/li>\r\n    <li>\u9752\u67f3\u5171\u592a\u3001\u4eca\u6cc9\u7f8e\u4f73 (2020)\u3000\uff12\u76f8\u6027\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u3000\u6708\u520a\u7cd6\u5c3f\u75c5, 127:20-26<\/li>\r\n    <li>\u4eca\u6cc9\u7f8e\u4f73 (2019)\u3000\u81b5\u03b2\u7d30\u80de\u306e\u30a2\u30af\u30c6\u30a3\u30d6\u30be\u30fc\u30f3\u30bf\u30f3\u30d1\u30af\u8ceaELKS\u304c\u8840\u7ba1\u65b9\u5411\u3078\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u6975\u6027\u5206\u6ccc\u3092\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3059\u308b\u3000Diabetes Journal, 47:168-170<\/li>\r\n    <li>\u4eca\u6cc9\u7f8e\u4f73 (2019)\u3000\u30a2\u30af\u30c6\u30a3\u30d6\u30be\u30fc\u30f3\u30bf\u30f3\u30d1\u30af\u8ceaELKS\u306b\u3088\u308b\u30a4\u30f3\u30b9\u30ea\u30f3\u6975\u6027\u5206\u6ccc\u8abf\u7bc0\u6a5f\u69cb\u3000Diabetes Strategy, 9:156-157<\/li>\r\n  <\/ol>\r\n<\/section>\r\n","protected":false},"excerpt":{"rendered":"<p>\u6559\u5ba4\u30db\u30fc\u30e0\u30da\u30fc\u30b8 \u6559\u5ba4\u5c02\u4efb\u6559\u54e1 \u6559\u5ba4\u6982\u8981 \u7d30\u80de\u751f\u5316\u5b66\u6559\u5ba4\u304c\u62c5\u5f53\u3059\u308b\u5206\u5b50\u751f\u7269\u5b66\u3001\u7d30\u80de\u751f\u7269\u5b66\u306f\u3001\u533b\u5b66\u30fb\u533b\u7642\u306e\u5168\u5206\u91ce\u306b\u6e21\u3063\u3066\u6280\u8853\u7684\u30fb\u6982\u5ff5\u7684\u306b\u305d\u308c\u3089\u306e\u652f\u67f1\u3068\u306a\u3063\u3066\u3044\u308b\u5b66\u554f\u3067\u3042\u308a\u3001\u8fd1\u5e74\u306e\u7d44\u307f\u63db\u3048DNA\u9769\u547d\u3092\u7d4c\u3066\u7206\u767a\u7684\u306a\u767a\u5c55\u3092\u9042\u3052\u3066 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":24,"menu_order":60,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"section":[4],"class_list":["post-101","page","type-page","status-publish","hentry","section-basics"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/pages\/101","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/comments?post=101"}],"version-history":[{"count":11,"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/pages\/101\/revisions"}],"predecessor-version":[{"id":7267,"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/pages\/101\/revisions\/7267"}],"up":[{"embeddable":true,"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/pages\/24"}],"wp:attachment":[{"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/media?parent=101"}],"wp:term":[{"taxonomy":"section","embeddable":true,"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/section?post=101"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}