{"id":103,"date":"2022-02-15T15:09:01","date_gmt":"2022-02-15T06:09:01","guid":{"rendered":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/_manage\/?page_id=103"},"modified":"2024-08-10T17:26:04","modified_gmt":"2024-08-10T08:26:04","slug":"pharmacology","status":"publish","type":"page","link":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/education\/labo\/pharmacology\/","title":{"rendered":"\u85ac\u7406\u5b66\u6559\u5ba4"},"content":{"rendered":"<section class=\"BlkAnchorArea\"><div class=\"BlkAnchorArea__inner\"><ul class=\"anchorMenu\"><li><a class=\"p-anchor\" href=\"#teacher\"><span>\u6559\u54e1<\/span><\/a><\/li><li><a class=\"p-anchor\" href=\"#summary\"><span>\u6982\u8981<\/span><\/a><\/li><li><a class=\"p-anchor\" href=\"#study\"><span>\u7814\u7a76<\/span><\/a><\/li><li><a class=\"p-anchor\" href=\"#achieve\"><span>\u696d\u7e3e<\/span><\/a><\/li><\/ul><\/div><\/section>\r\n<section class=\"BlkArticle__Contents--notLead\">\r\n  <div class=\"BlkArticle__btnlink--multi\">\r\n    <div class=\"BlkArticle__btnlink\">\r\n      <p><a class=\"u-icon_blank\" href=\"https:\/\/www.kyorin-u.ac.jp\/univ\/user\/medicine\/pharmaco\/\" target=\"_blank\" rel=\"noopener\"><span>\u6559\u5ba4\u30db\u30fc\u30e0\u30da\u30fc\u30b8<\/span><\/a><\/p>\r\n    <\/div>\r\n  <\/div>\r\n<\/section>\r\n<a id=\"teacher\" name=\"teacher\"><\/a>\r\n<section class=\"BlkArticle__Contents BlkArticle__Contents--notLead\">\r\n  <h2>\u6559\u5ba4\u5c02\u4efb\u6559\u54e1<\/h2>\r\n  \n<!-- staffdb 2023.08.15 -->\n<div><table class=\"BlkArticle__tableNormal BlkArticle__tableNormal--topLeft\" width=\"100%\" data-update=\"2023.08.15\"><tbody><tr><th>\u6559\u6388<\/th><td><ul class=\"list-on-td\"><li data-sort=\"90000\uff0f50001\"><a href=\"\/univ\/faculty\/medicine\/education\/staffnew\/detail\/?id=med50001\" class=\"arrow\">\u6afb\u4e95\u3000\u88d5\u4e4b<\/a><\/li><\/ul><\/td><\/tr><tr><th>\u52a9\u6559<\/th><td><ul class=\"list-on-td\"><li data-sort=\"70\uff0f50005\"><a href=\"\/univ\/faculty\/medicine\/education\/staffnew\/detail\/?id=med50005\" class=\"arrow\">\u798f\u51a8\u3000\u4fca\u4e4b<\/a><\/li><li data-sort=\"60\uff0f50007\"><a href=\"\/univ\/faculty\/medicine\/education\/staffnew\/detail\/?id=med50007\" class=\"arrow\">\u5805\u7530\u3000\u667a\u4e45<\/a><\/li><li data-sort=\"0\uff0f50009\"><a href=\"\/univ\/faculty\/medicine\/education\/staffnew\/detail\/?id=med50009\" class=\"arrow\">\u7530\u4e2d\u3000\u5f26<\/a><\/li><li data-sort=\"0\uff0f50010\"><a href=\"\/univ\/faculty\/medicine\/education\/staffnew\/detail\/?id=med50010\" class=\"arrow\">\u672b\u5f18\u3000\u6df3\u4e00<\/a><\/li><\/ul><\/td><\/tr><\/tbody><\/table><\/div> <\/section>\r\n<a id=\"summary\" name=\"summary\"><\/a>\r\n<section class=\"BlkArticle__Contents BlkArticle__Contents--notLead\">\r\n  <h2>\u6559\u5ba4\u6982\u8981<\/h2>\r\n  <p>\u6559\u80b2\u9762\u3067\u306f\u3001\u533b\u5b66\u90e8\uff13\u5e74\u524d\u671f\u306e\u85ac\u7406\u5b66\u8b1b\u7fa9\u30fb\u5b9f\u7fd2\u3068\uff14\u5e74\u5f8c\u671f\u306e\u548c\u6f22\u533b\u5b66\u6982\u8ad6\u3092\u62c5\u5f53\u3057\u3066\u3044\u308b\u3002<\/p>\r\n<\/section>\r\n<section class=\"BlkArticle__Contents BlkArticle__Contents--notLead\">\r\n  <h2>\u6559\u80b2\u306e\u7279\u8272<\/h2>\r\n  <p>\u57fa\u790e\u533b\u5b66\u306e\u7dcf\u307e\u3068\u3081\u3068\u81e8\u5e8a\u533b\u5b66\u3078\u306e\u6a4b\u6e21\u3057\u3092\u610f\u8b58\u3057\u305f\u8b1b\u7fa9\u3092\u3057\u3066\u3044\u308b\u3002\u52d5\u7269\u7d44\u7e54\u3092\u4f7f\u3063\u305f\u5b9f\u7fd2\u306b\u3088\u308a\u85ac\u7269\u304c\u751f\u4f53\u306b\u3069\u3046\u50cd\u304f\u306e\u304b\u3092\u5b9f\u5730\u4f53\u9a13\u3067\u304d\u308b\u3002<\/p>\r\n<\/section>\r\n<section class=\"BlkArticle__Contents BlkArticle__Contents--notLead\">\r\n  <h2>\u793e\u4f1a\u7684\u6d3b\u52d5<\/h2>\r\n  <p>\u65e5\u672c\u85ac\u7406\u5b66\u4f1a\u3001\u65e5\u672c\u814e\u81d3\u5b66\u4f1a\u3001\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u3001\u65e5\u672c\u75db\u98a8\u6838\u9178\u4ee3\u8b1d\u5b66\u4f1a\u3001\u65e5\u672c\u764c\u5b66\u4f1a\u3001\u7c73\u56fd\u814e\u81d3\u5b66\u4f1a(ASN)\u3001\u7c73\u56fd\u7d30\u80de\u751f\u7269\u5b66\u4f1a(ASCB)\u7b49\u306b\u6240\u5c5e\u3057\u3001\u7814\u7a76\u767a\u8868\u3092\u884c\u3063\u3066\u3044\u308b\u3002<\/p>\r\n<\/section>\r\n<a id=\"study\" name=\"study\"><\/a>\r\n<section class=\"BlkArticle__Contents BlkArticle__Contents--notLead\">\r\n  <h2>\u7814\u7a76\u30c6\u30fc\u30de<\/h2>\r\n  <h3>\u30a2\u30df\u30ce\u9178\u30c8\u30e9\u30f3\u30b9\u30dd\u30fc\u30bf\u30fc\u306e\u751f\u7406\u7684\u30fb\u75c5\u7406\u7684\u5f79\u5272\u306e\u89e3\u660e<\/h3>\r\n  <p>\u30a2\u30df\u30ce\u9178\u30c8\u30e9\u30f3\u30b9\u30dd\u30fc\u30bf\u30fc\u306e\u4e2d\u3067\u3082\u80ce\u5150\u3084\u304c\u3093\u7d30\u80de\u3067\u767a\u73fe\u306e\u591a\u3044LAT1\u3092\u4e2d\u5fc3\u306b\u3001\u767a\u751f\u3001\u304c\u3093\u3001\u8840\u7ba1\u65b0\u751f\u306a\u3069\u69d8\u3005\u306a\u751f\u7406\u7684\u3001\u75c5\u7406\u7684\u30d7\u30ed\u30bb\u30b9\u306b\u304a\u3044\u3066\u3001\u3069\u306e\u3088\u3046\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u308b\u306e\u304b\u3092\u7814\u7a76\u3057\u3066\u3044\u308b\u3002\u307e\u305f\u3001\u3053\u306e\u30c8\u30e9\u30f3\u30b9\u30dd\u30fc\u30bf\u30fc\u306e\u963b\u5bb3\u304c\u304c\u3093\u3068\u305d\u306e\u5fae\u5c0f\u74b0\u5883\u306b\u3069\u306e\u3088\u3046\u306a\u5f71\u97ff\u3092\u53ca\u307c\u3059\u304b\u3092\u691c\u8a0e\u3057\u3066\u3044\u308b\u3002<\/p>\r\n  <h3>\u5c3f\u9178\u8f38\u9001\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u89e3\u660e<\/h3>\r\n  <p>\u30d2\u30c8\u3067\u306f\u30d7\u30ea\u30f3\u4f53\u306e\u6700\u7d42\u4ee3\u8b1d\u7523\u7269\u3067\u3042\u308b\u5c3f\u9178\u306f\u814e\u81d3\u304b\u3089\u6392\u6cc4\u3055\u308c\u308b\u304c\u3001\u305d\u306e\u904e\u7a0b\u306b\u95a2\u4e0e\u3059\u308b\u30c8\u30e9\u30f3\u30b9\u30dd\u30fc\u30bf\u30fc\u306e\u6a5f\u80fd\u3092\u89e3\u660e\u3059\u308b\u3002<\/p>\r\n  <h3>\u814e\u5c3f\u7d30\u7ba1\u306e\u5206\u5316\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u89e3\u660e<\/h3>\r\n  <p>\u30a2\u30d5\u30ea\u30ab\u30c4\u30e1\u30ac\u30a8\u30eb\u306e\u524d\u814e\u3092\u30e2\u30c7\u30eb\u306b\u5c3f\u7d30\u7ba1\u306e\u30bb\u30b0\u30e1\u30f3\u30c8\u304c\u3069\u306e\u3088\u3046\u306b\u5206\u5316\u3057\u3066\u3044\u304f\u306e\u304b\u3092\u89e3\u660e\u3059\u308b\u3002<\/p>\r\n<\/section>\r\n<a id=\"achieve\" name=\"achieve\"><\/a>\r\n<section class=\"BlkArticle__Contents BlkArticle__Contents--notLead\">\r\n  <h2>\u8fd1\u5e74\u306e\u4e3b\u306a\u696d\u7e3e<\/h2>\r\n  <ol class=\"BlkArticle__listNumber\">\r\n    <li>Induction of CTH expression in response to amino acid starvation confers resistance to anti-LAT1 therapy in MDA-MB-231 cells.<br>\r\n      Yamaga T, Suehiro J, Wada Y1, Sakurai H<br>\r\n      <i>Sci Rep.<\/i> <b>12,<\/b> 1021 (2022)<\/li>\r\n    <li>Xenopus slc7a5 is essential for notochord function and eye development.<br>\r\n      Katada T, Sakurai H<br>\r\n      <i>Mech Dev.<\/i> <b>155,<\/b> 48-59 (2019)<\/li>\r\n    <li>Urate Transport via Paracellular Route across Epithelial Cells.<br>\r\n      Kimura T, Tsukada A, Fukutomi T, Ichida K, Ohtsuki S, Sakurai H<br>\r\n      <i>Biol Pharm Bull.<\/i> <b>42,<\/b> 43-49 (2019)<\/li>\r\n    <li>Prostate Cancer Cells in Different Androgen Receptor Status Employ Different Leucine Transporters.<br>\r\n      Otsuki H, Kimura T, Yamaga T, Kosaka T, Suehiro JI, Sakurai H.<br>\r\n      <i>Prostate.<\/i> <b>77,<\/b> 222-233 (2017)<\/li>\r\n    <li>Expression of SLC2A9 Isoforms in the Kidney and Their Localization in Polarized Epithelial Cells.<br>\r\n      Kimura T, Takahashi M, Yan K, Sakurai H.<br>\r\n      <i>PLoS One<\/i> <b>9,<\/b> e84996 (2014)<\/li>\r\n  <\/ol>\r\n  <p class=\"BlkArticle__txtlink\"><a href=\"https:\/\/www.kyorin-u.ac.jp\/univ\/user\/medicine\/pharmaco\/index.html\" target=\"_blank\" class=\"u-icon_blank u-mgt_40\" rel=\"noopener\">\u5f53\u6559\u5ba4\u306e\u8a73\u7d30\u306f\u3001\u85ac\u7406\u5b66\u6559\u5ba4\u306e\u30db\u30fc\u30e0\u30da\u30fc\u30b8\u307e\u3067\u3002<\/a><\/p>\r\n<\/section>","protected":false},"excerpt":{"rendered":"<p>\u6559\u5ba4\u30db\u30fc\u30e0\u30da\u30fc\u30b8 \u6559\u5ba4\u5c02\u4efb\u6559\u54e1 \u6559\u5ba4\u6982\u8981 \u6559\u80b2\u9762\u3067\u306f\u3001\u533b\u5b66\u90e8\uff13\u5e74\u524d\u671f\u306e\u85ac\u7406\u5b66\u8b1b\u7fa9\u30fb\u5b9f\u7fd2\u3068\uff14\u5e74\u5f8c\u671f\u306e\u548c\u6f22\u533b\u5b66\u6982\u8ad6\u3092\u62c5\u5f53\u3057\u3066\u3044\u308b\u3002 \u6559\u80b2\u306e\u7279\u8272 \u57fa\u790e\u533b\u5b66\u306e\u7dcf\u307e\u3068\u3081\u3068\u81e8\u5e8a\u533b\u5b66\u3078\u306e\u6a4b\u6e21\u3057\u3092\u610f\u8b58\u3057\u305f\u8b1b\u7fa9\u3092\u3057\u3066\u3044\u308b\u3002\u52d5\u7269\u7d44\u7e54\u3092\u4f7f\u3063\u305f [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":24,"menu_order":70,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"section":[4],"class_list":["post-103","page","type-page","status-publish","hentry","section-basics"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/pages\/103","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/comments?post=103"}],"version-history":[{"count":7,"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/pages\/103\/revisions"}],"predecessor-version":[{"id":5661,"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/pages\/103\/revisions\/5661"}],"up":[{"embeddable":true,"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/pages\/24"}],"wp:attachment":[{"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/media?parent=103"}],"wp:term":[{"taxonomy":"section","embeddable":true,"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/section?post=103"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}