{"id":112,"date":"2022-02-15T15:25:28","date_gmt":"2022-02-15T06:25:28","guid":{"rendered":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/_manage\/?page_id=112"},"modified":"2025-06-25T16:23:41","modified_gmt":"2025-06-25T07:23:41","slug":"biology","status":"publish","type":"page","link":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/education\/labo\/biology\/","title":{"rendered":"\u751f\u7269\u5b66\u6559\u5ba4"},"content":{"rendered":"<section class=\"BlkAnchorArea\"><div class=\"BlkAnchorArea__inner\"><ul class=\"anchorMenu\"><li><a class=\"p-anchor\" href=\"#teacher\"><span>\u6559\u54e1<\/span><\/a><\/li><li><a class=\"p-anchor\" href=\"#summary\"><span>\u6982\u8981<\/span><\/a><\/li><li><a class=\"p-anchor\" href=\"#study\"><span>\u7814\u7a76<\/span><\/a><\/li><li><a class=\"p-anchor\" href=\"#achieve\"><span>\u696d\u7e3e<\/span><\/a><\/li><\/ul><\/div><\/section> \r\n<!--section class=\"BlkArticle__Contents--notLead\">\r\n  <div class=\"BlkArticle__btnlink--multi\">\r\n    <div class=\"BlkArticle__btnlink\">\r\n      <p><a class=\"u-icon_blank\" href=\"https:\/\/www.kyorin-u.ac.jp\/univ\/user\/medicine\/seibutsu\/iWeb_Bio\/Top.html\" target=\"_blank\" rel=\"noopener\"><span>\u6559\u5ba4\u30db\u30fc\u30e0\u30da\u30fc\u30b8<\/span><\/a><\/p>\r\n    <\/div>\r\n  <\/div>\r\n<\/section--> \r\n<a id=\"teacher\" name=\"teacher\"><\/a>\r\n<section class=\"BlkArticle__Contents BlkArticle__Contents--notLead\">\r\n  <h2>\u6559\u5ba4\u5c02\u4efb\u6559\u54e1<\/h2>\r\n  \n<!-- staffdb 2023.08.15 -->\n<div><table class=\"BlkArticle__tableNormal BlkArticle__tableNormal--topLeft\" width=\"100%\" data-update=\"2023.08.15\"><tbody><tr><th>\u6559\u6388<\/th><td><ul class=\"list-on-td\"><li data-sort=\"0\uff0f56006\"><a href=\"\/univ\/faculty\/medicine\/education\/staffnew\/detail\/?id=med56006\" class=\"arrow\">\u7c9f\u5d0e\u3000\u5065<\/a><\/li><\/ul><\/td><\/tr><tr><th>\u51c6\u6559\u6388<\/th><td><ul class=\"list-on-td\"><li data-sort=\"0\uff0f56005\"><a href=\"\/univ\/faculty\/medicine\/education\/staffnew\/detail\/?id=med56005\" class=\"arrow\">\u5e73\u4e95\u3000\u548c\u4e4b<\/a><\/li><li data-sort=\"0\uff0f56007\"><a href=\"\/univ\/faculty\/medicine\/education\/staffnew\/detail\/?id=med56007\" class=\"arrow\">\u52a0\u85e4\u3000\u5065\u592a\u90ce<\/a><\/li><\/ul><\/td><\/tr><\/tbody><\/table><\/div> <\/section>\r\n<a id=\"summary\" name=\"summary\"><\/a>\r\n<section class=\"BlkArticle__Contents BlkArticle__Contents--notLead\">\r\n  <h2>\u6559\u5ba4\u6982\u8981<\/h2>\r\n  <p>\u533b\u5b66\u90e8\u751f\u7269\u5b66\u6559\u5ba4\u306f\u3001\u662d\u548c\uff14\uff15\u5e74\uff14\u6708\u306b\u767a\u8db3\u4ee5\u6765\u3001\u690d\u6751\u5229\u592b\u3001\u5927\u5ddd\u771f\u6f84\u3001\u5289\u9038\u6c11\u3001\u68ee\u5143\u3001\u677e\u7530\u5b97\u7537\u306e\u6b74\u4ee3\u6559\u6388\u306b\u3088\u3063\u3066\u5f15\u304d\u7d9a\u304d\u3064\u304c\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u5e73\u6210\uff12\uff16\u5e74\uff13\u6708\u306b\u677e\u7530\u5b97\u7537\u6559\u6388\u304c\u5b9a\u5e74\u3092\u8fce\u3048\u3001\u540c\u5e74\uff14\u6708\u3088\u308a\u7c9f\u5d0e\u5065\u304c\u6559\u6388\u3068\u306a\u308a\u3001\u73fe\u5728\u306f\u3001\u5e73\u4e95\u548c\u4e4b\u8b1b\u5e2b\u3001\u52a0\u85e4\u5065\u592a\u90ce\u8b1b\u5e2b\u306e\uff13\u540d\u306b\u3088\u308a\u751f\u7269\u5b66\u6559\u5ba4\u3092\u904b\u55b6\u3057\u3066\u3044\u307e\u3059\u3002\u5404\u6559\u54e1\u306f\u3001\u907a\u4f1d\u5b66\u3001\u5206\u5b50\u751f\u7269\u5b66\u3001\u767a\u751f\u5b66\u3001\u795e\u7d4c\u79d1\u5b66\u306e\u5206\u91ce\u3067\u306e\u7814\u7a76\u3092\u884c\u3044\u3001\u5b66\u5185\u3060\u3051\u3067\u306a\u304f\u5b66\u5916\u306e\u7814\u7a76\u8005\u3068\u9023\u643a\u3057\u69d8\u3005\u306a\u5171\u540c\u7814\u7a76\u3092\u5c55\u958b\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\r\n<\/section>\r\n<section class=\"BlkArticle__Contents BlkArticle__Contents--notLead\">\r\n  <h2>\u6559\u80b2\u306e\u7279\u8272<\/h2>\r\n  <p>\u751f\u7269\u5b66\u6559\u5ba4\u306f\u3001\u4e3b\u306b\u533b\u5b66\u90e8\u521d\u5e74\u5ea6\u5b66\u751f(M1)\u306b\u5bfe\u3059\u308b\u6559\u80b2\u3092\u62c5\u5f53\u3057\u3066\u3044\u307e\u3059\u3002\u300c\u5165\u9580\u751f\u7269\u5b66\u300d\u3001\u300c\u751f\u7269\u5b66\u300d\u3001\u300c\u751f\u7269\u5b66\u5b9f\u7fd2\u300d\u3001\u300c\u5206\u5b50\u751f\u7269\u5b66\u300d\u306e\u62c5\u5f53\u3001\u306a\u3089\u3073\u306b\u300c\u30d7\u30ec\u30c1\u30e5\u30fc\u30c8\u30ea\u30a2\u30eb\u6559\u80b2\u300d\u306e\u904b\u55b6\u3068\u30c1\u30e5\u30fc\u30bf\u30fc\u3092\u62c5\u5f53\u3057\u3066\u3044\u307e\u3059\u3002\u307e\u305fM1\u5b66\u751f\u306e\u62c5\u4efb\u3092\u62c5\u5f53\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\r\n<\/section>\r\n<section class=\"BlkArticle__Contents BlkArticle__Contents--notLead\">\r\n  <h2>\u793e\u4f1a\u7684\u6d3b\u52d5<\/h2>\r\n  <p>\u5e73\u621014\u5e74\u5ea6\u3088\u308a\u300c\u30ca\u30b7\u30e7\u30ca\u30eb\u30d0\u30a4\u30aa\u30ea\u30bd\u30fc\u30b9\u30d7\u30ed\u30b8\u30a7\u30af\u30c8(NBRP)\u3001\u30b7\u30e7\u30a6\u30b8\u30e7\u30a6\u30d0\u30a8\u300d\u306e\u30b5\u30d6\u6a5f\u95a2\u3068\u3057\u3066\u6d3b\u52d5\u3057\u3066\u6765\u307e\u3057\u305f\u3002\u4ee4\u548c\uff14\u5e74\u5ea6\u3088\u308a\u65b0\u305f\u306b\uff15\u5e74\u9593\u3001\u7b2c\uff15\u671fNBRP\u30fb\u30b7\u30e7\u30a6\u30b8\u30e7\u30a6\u30d0\u30a8\uff08\u6587\u90e8\u79d1\u5b66\u7701\uff09\u306e\u4e2d\u6838\u6a5f\u95a2\u3068\u3057\u3066\u300c\u30b7\u30e7\u30a6\u30b8\u30e7\u30a6\u30d0\u30a8\u8fd1\u7e01\u7a2e\u907a\u4f1d\u8cc7\u6e90\u306e\u6226\u7565\u7684\u53ce\u96c6\u30fb\u7dad\u6301\u7ba1\u7406\u3068\u63d0\u4f9b 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<p>\u7c9f\u5d0e\u3001\u52a0\u85e4\u306f\u3001\u30b7\u30e7\u30a6\u30b8\u30e7\u30a6\u30d0\u30a8\u8133\u30fb\u4e2d\u67a2\u7d44\u7e54\u7cfb\u3092\u30e2\u30c7\u30eb\u5b9f\u9a13\u7cfb\u306b\u7528\u3044\u3066\u3001\u795e\u7d4c\u7cfb\u306e\u767a\u751f\u5206\u5316\u30fb\u6a5f\u80fd\u30fb\u9032\u5316\u3068\u795e\u7d4c-\u30b0\u30ea\u30a2\u76f8\u4e92\u4f5c\u7528\u306b\u7740\u76ee\u3057\u305f\u7814\u7a76\u3092\u5c55\u958b\u3057\u3066\u3044\u307e\u3059\u3002\u5e73\u4e95\u306f\u3001\u6709\u6027\u751f\u6b96\u306b\u304a\u3051\u308b\u53d7\u7cbe\u4f9d\u5b58\u7684\u306a\u767a\u751f\u958b\u59cb\u6a5f\u69cb\u306b\u95a2\u3057\u3066\u3001\u30a2\u30ca\u30ca\u30b9\u30b7\u30e7\u30a6\u30b8\u30e7\u30a6\u30d0\u30a8\u306e\u5358\u70ba\u751f\u6b96\u7cfb\u7d71\u3092\u5229\u7528\u3057\u305f\u7814\u7a76\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u4ed6\u3001\u30b7\u30e7\u30a6\u30b8\u30e7\u30a6\u30d0\u30a8\u8fd1\u7e01\u7a2e\u306b\u304a\u3051\u308b\u74b0\u5883\u5fdc\u7b54\u3068\u795e\u7d4c\u7cfb\u306e\u9032\u5316\u306e\u7814\u7a76\u3084\u3001\u30b7\u30e7\u30a6\u30b8\u30e7\u30a6\u30d0\u30a8\u907a\u4f1d\u5b66\u7684\u89e3\u6790\u30c4\u30fc\u30eb\u306e\u958b\u767a\u7b49\u3082\u884c\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\r\n  <h3>\u5b66\u5916\u3068\u306e\u5171\u540c\u7814\u7a76<\/h3>\r\n  <p>\u7c9f\u5d0e\u306fHoward Hughes Medical Institute, Janelia Research Campus (Tzumin Lee\u535a\u58eb\uff09\u3068\u8133\u795e\u7d4c\u7cfb\u306e\u767a\u751f\u3068\u6a5f\u80fd\u306b\u95a2\u3059\u308b\u5171\u540c\u7814\u7a76\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u30b0\u30ea\u30a2\u6a5f\u80fd\u306e\u7814\u7a76\u306b\u3064\u3044\u3066\u306f\u56fd\u7acb\u907a\u4f1d\u5b66\u7814\u7a76\u6240\u3068\u5171\u540c\u7814\u7a76\u3092\u5c55\u958b\u3057\u3066\u3044\u307e\u3059\u3002\u30b7\u30e7\u30a6\u30b8\u30e7\u30a6\u30d0\u30a8\u8fd1\u7e01\u7a2e\u3092\u5229\u7528\u3057\u305f\u7814\u7a76\u306b\u3064\u3044\u3066\u306f\u3001\u4eac\u90fd\u5de5\u82b8\u7e4a\u7dad\u5927\u5b66\u3001\u6771\u4eac\u5927\u5b66\u3001\u540d\u53e4\u5c4b\u5927\u5b66\u3001\u7b51\u6ce2\u5927\u5b66\u3001\u3068\u7814\u7a76\u89e3\u6790\u30c4\u30fc\u30eb\u306e\u5171\u540c\u958b\u767a\u3068\u5171\u540c\u7814\u7a76\u3092\u5c55\u958b\u3057\u3066\u3044\u307e\u3059\u3002\u5e73\u4e95\u306f\u3001\u5358\u70ba\u751f\u6b96\u7cfb\u7d71\u306e\u30b2\u30ce\u30e0\u89e3\u6790\u3092\u56fd\u7acb\u907a\u4f1d\u5b66\u7814\u7a76\u6240\u3068\u3001\u307e\u305f\u4e2d\u5fc3\u4f53\u306e\u8d85\u89e3\u50cf\u9855\u5fae\u93e1\u89e3\u6790\u3092\u4eac\u90fd\u5de5\u82b8\u7e4a\u7dad\u5927\u5b66\u3068\u5171\u540c\u3067\u884c\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\r\n<\/section>\r\n<a id=\"achieve\" name=\"achieve\"><\/a>\r\n<section class=\"BlkArticle__Contents BlkArticle__Contents--notLead\">\r\n  <h2>\u8fd1\u5e74\u306e\u4e3b\u306a\u696d\u7e3e<\/h2>\r\n  <ol class=\"BlkArticle__listNumber\">\r\n    <li>Ito F and <b>Awasaki T<\/b> (2022). Comparative analysis of temperature preference behavior and effects of temperature on daily behavior in eleven <i>Drosophila<\/i> species. <b>Sci Repo<\/b> 12:12692<\/li>\r\n    <li><b>Kato K<\/b>, Orihara-Ono M, <b>Awasaki T<\/b> (2020). Multiple lineages enable robust development of the neuropil-glia architecture in adult <i>Drosophila<\/i>. <b>Development<\/b> 147: dev184085<\/li>\r\n    <li><b>Hirai K<\/b>, et al (2018). Genetic analyses of <i>Elys<\/i> mutations in Drosophila show maternal-effect lethality and interactions with Nucleoporin genes. <b>G3<\/b> 8:2421-2431<\/li>\r\n    <li>Ren Q, <b>Awasaki T<\/b>, et al (2018). Lineage-guided Notch-dependent gliogenesis by Drosophila multi-potent progenitors. <b>Development<\/b> 145: dev160127<\/li>\r\n    <li><b>Kato K<\/b>, et al (2017). Gene network underlying the glial regenerative response to central nervous system injury. <b>Dev Dyn<\/b> 247(1), 85 8-93<\/li>\r\n    <li><b>Awasaki T<\/b> and Ito K (2016). Regeneration switch is a gas. <b>Nature<\/b> 531,182-3<\/li>\r\n    <li>Ren Q, <b>Awasaki T<\/b>, et al (2016). Cell Class-Lineage Analysis Reveals Sexually Dimorphic Lineage Compositions in the Drosophila Brain. <b>Curr Biol<\/b> 26, 2583-2593<\/li>\r\n    <li><b>Kato K<\/b> et al., (2015). A. Prox1 Inhibits Proliferation and Is Required for Differentiation of the Oligodendrocyte Cell Lineage in the Mouse. <b>PLoS ONE<\/b> e0145334.<\/li>\r\n    <li><b>Awasaki T<\/b>, et al (2014). Making Drosophila lineage-restricted drivers via patterned recombination in neuroblasts. <b>Nature Neurosci<\/b> 17, 631-7<\/li>\r\n    <li><b>Awasaki T<\/b>, et al (2011). Glial cell-derived TGF-\u00df ligand, Myoglianin, regulates developmental remodeling of larval neural circuits in Drosophila. <b>Nature Neurosci<\/b> 14, 821-3<\/li>\r\n    <li><b>Kato K<\/b>, et al (2011). The glial regenerative response to central nervous system injury is enabled by pros-notch and pros-NF\u03baB feedback. <b>PLoS Biol<\/b> e1001133<\/li>\r\n    <li>Muramatsu S, <b>Hirai K<\/b>, et al (2010) CDK-dependent complex formation between replication proteins Dpb11, Sld2, Pol \u03b5, and GINS in budding yeast. Genes Dev. 24:602-612<\/li>\r\n  <\/ol>\r\n  <!--p class=\"BlkArticle__txtlink\"><a href=\"https:\/\/www.kyorin-u.ac.jp\/univ\/user\/medicine\/seibutsu\/iWeb_Bio\/Top.html\" target=\"_blank\" class=\"u-icon_blank u-mgt_40\" rel=\"noopener\">\u5f53\u6559\u5ba4\u306e\u8a73\u7d30\u306f\u3001\u751f\u7269\u5b66\u6559\u5ba4\u306e\u30db\u30fc\u30e0\u30da\u30fc\u30b8\u3078\u3002<\/a><\/p--> \r\n<\/section>\r\n","protected":false},"excerpt":{"rendered":"<p>\u6559\u5ba4\u5c02\u4efb\u6559\u54e1 \u6559\u5ba4\u6982\u8981 \u533b\u5b66\u90e8\u751f\u7269\u5b66\u6559\u5ba4\u306f\u3001\u662d\u548c\uff14\uff15\u5e74\uff14\u6708\u306b\u767a\u8db3\u4ee5\u6765\u3001\u690d\u6751\u5229\u592b\u3001\u5927\u5ddd\u771f\u6f84\u3001\u5289\u9038\u6c11\u3001\u68ee\u5143\u3001\u677e\u7530\u5b97\u7537\u306e\u6b74\u4ee3\u6559\u6388\u306b\u3088\u3063\u3066\u5f15\u304d\u7d9a\u304d\u3064\u304c\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u5e73\u6210\uff12\uff16\u5e74\uff13\u6708\u306b\u677e\u7530\u5b97\u7537\u6559\u6388\u304c\u5b9a\u5e74\u3092\u8fce\u3048\u3001\u540c\u5e74\uff14\u6708\u3088\u308a\u7c9f\u5d0e\u5065\u304c\u6559 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":24,"menu_order":120,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"section":[4],"class_list":["post-112","page","type-page","status-publish","hentry","section-basics"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/pages\/112","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/comments?post=112"}],"version-history":[{"count":9,"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/pages\/112\/revisions"}],"predecessor-version":[{"id":7187,"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/pages\/112\/revisions\/7187"}],"up":[{"embeddable":true,"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/pages\/24"}],"wp:attachment":[{"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/media?parent=112"}],"wp:term":[{"taxonomy":"section","embeddable":true,"href":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/wp-json\/wp\/v2\/section?post=112"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}