{"id":1926,"date":"2019-10-21T15:12:56","date_gmt":"2019-10-21T06:12:56","guid":{"rendered":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/_manage\/news\/1926\/"},"modified":"2025-07-11T09:49:51","modified_gmt":"2025-07-11T00:49:51","slug":"%e9%80%8f%e6%98%8e%e3%83%a1%e3%83%80%e3%82%ab%e3%81%ab%e3%82%88%e3%81%a3%e3%81%a6%e3%80%81%e4%bd%93%e5%86%85%e3%81%ab%e5%85%a5%e3%81%a3%e3%81%9f%e3%83%9e%e3%82%a4%e3%82%af%e3%83%ad%e3%83%97%e3%83%a9","status":"publish","type":"post","link":"https:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/archive\/1926\/","title":{"rendered":"\u900f\u660e\u30e1\u30c0\u30ab\u306b\u3088\u3063\u3066\u3001\u4f53\u5185\u306b\u5165\u3063\u305f\u30de\u30a4\u30af\u30ed\u30d7\u30e9\u30b9\u30c1\u30c3\u30af\u30d3\u30fc\u30ba\u306e\u751f\u4f53\u3078\u306e\u5f71\u97ff\u304c\u660e\u3089\u304b\u306b"},"content":{"rendered":"<div align=\"right\">\r\n<p><b>\r\n\u82e3\u7530\u3000\u614e\u4e00\u3000\uff08\u885b\u751f\u5b66\u516c\u8846\u885b\u751f\u5b66\u6559\u5ba4\u3000\u52a9\u6559\uff09\u3000<br \/>\r\n\u5409\u7530\u3000\u6b63\u96c4\u3000\uff08\u885b\u751f\u5b66\u516c\u8846\u885b\u751f\u5b66\u6559\u5ba4\u3000\u51c6\u6559\u6388\uff09<br \/>\r\n\u82c5\u7530\u3000\u9999\u82d7\u3000\uff08\u885b\u751f\u5b66\u516c\u8846\u885b\u751f\u5b66\u6559\u5ba4\u3000\u6559\u6388\uff09\u3000<br \/>\r\n<\/b><\/p>\r\n<\/div>\r\n\r\n<h5>\u7814\u7a76\u306e\u30cf\u30a4\u30e9\u30a4\u30c8<\/h5>\r\n<ul>\r\n\r\n<li>\u6c34\u57df\u74b0\u5883\u4e2d\u3067\u66dd\u9732\u3055\u308c\u5f97\u308b\u91cf\u306e\u30de\u30a4\u30af\u30ed\u30d7\u30e9\u30b9\u30c1\u30c3\u30af\u30d3\u30fc\u30ba\uff08\u30dd\u30ea\u30a8\u30c1\u30ec\u30f3\u88fd\u3001\u7c92\u5f8460\u03bcm\u4ee5\u4e0b\uff09\u3092\u3001\u30e1\u30c0\u30ab\u306b12\u9031\u9593\u7d4c\u53e3\u6442\u53d6\u3055\u305b\u305f\u3002<\/li>\r\n<li>\u3053\u306e\u66dd\u9732\u306b\u3088\u308a\u3001\u30e1\u30c0\u30ab\u306e\u6210\u9577\u7387\u3001\u7523\u5375\u6570\u3001\u5b75\u5316\u7387\u304c\u6e1b\u5c11\u3057\u305f\u3002<\/li>\r\n<li>\u6442\u53d6\u3055\u308c\u305f\u30de\u30a4\u30af\u30ed\u30d7\u30e9\u30b9\u30c1\u30c3\u30af\u30d3\u30fc\u30ba\u306f\u9577\u671f\u9593\u6d88\u5316\u7ba1\u306b\u7559\u307e\u3063\u3066\u3044\u305f\u3002<\/li>\r\n<li>\u30de\u30a4\u30af\u30ed\u30d7\u30e9\u30b9\u30c1\u30c3\u30af\u30d3\u30fc\u30ba\u306e\u6392\u6cc4\u3055\u308c\u306b\u304f\u3055\u304c\u3001\u6804\u990a\u963b\u5bb3\u3084\u305d\u306e\u4ed6\u306e\u751f\u4f53\u5f71\u97ff\u3092\u5f15\u304d\u8d77\u3053\u3057\u305f\u3068\u63a8\u6e2c\u3055\u308c\u305f\u3002<\/li>\r\n\r\n<\/ul>\r\n<br \/>\r\n\r\n<h5>\u6982\u8981<\/h5>\r\n<p>\u73fe\u5728\u3001\u30d7\u30e9\u30b9\u30c1\u30c3\u30af\u3054\u307f\u306e\u6c34\u74b0\u5883\u6c5a\u67d3\u304c\u554f\u984c\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u30a2\u30e1\u30ea\u30ab\u306e\u7814\u7a76\u30c1\u30fc\u30e0\u306e\u5831\u544a\u306b\u3088\u308b\u3068\u3001\u6c34\u9053\u6c34\u306b\u3082\u30de\u30a4\u30af\u30ed\u30d7\u30e9\u30b9\u30c1\u30c3\u30af\uff08\u4ee5\u4e0bMP\u3068\u8a18\u8f09\uff09\u7e4a\u7dad\u304c\u542b\u307e\u308c\u3066\u3044\u308b\u5834\u5408\u304c\u3042\u308a\u3001\u79c1\u305f\u3061\u3082\u98f2\u6c34\u7b49\u3092\u901a\u3058\u3066MP\u3092\u6442\u53d6\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002MP\u30d3\u30fc\u30ba\u306f\u6d17\u9854\u6599\u3084\u5316\u7ca7\u54c1\u306e\u30b9\u30af\u30e9\u30d6\u306e\u539f\u6750\u6599\u3068\u3057\u3066\u751f\u7523\u3055\u308c\u308b\u6570\u5341\u304b\u3089\u6570\u767e\u03bcm\u306e\u7c92\u5b50\u3067\u3001\u8a66\u7b97\u306b\u3088\u308b\u3068\u6bce\u65e58\u5146\u500b\u306eMP\u30d3\u30fc\u30ba\u304c\u6c34\u74b0\u5883\u306b\u6392\u51fa\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3068\u3053\u308d\u304c\u3001\u73fe\u5728\u306e\u3068\u3053\u308dMP\u306e\u751f\u4f53\u6bd2\u6027\u3092\u8a55\u4fa1\u3057\u305f\u7814\u7a76\u306f\u4e4f\u3057\u304f\u3001\u65e9\u6025\u306a\u7814\u7a76\u30c7\u30fc\u30bf\u306e\u96c6\u7a4d\u304c\u5f85\u305f\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\r\n\u3000\u79c1\u305f\u3061\u306e\u7814\u7a76\u3067\u306f\u3001MP\u3092\u5c0f\u578b\u810a\u690e\u52d5\u7269\u304c\u6442\u53d6\u3057\u305f\u5834\u5408\u3001\u751f\u4f53\u306b\u3069\u306e\u3088\u3046\u306a\u5f71\u97ff\u304c\u73fe\u308f\u308c\u308b\u306e\u304b\u3092\u5b9f\u9a13\u7684\u306b\u8abf\u3079\u307e\u3057\u305f\u3002\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u3001MP\u30d3\u30fc\u30ba\uff08\u30dd\u30ea\u30a8\u30c1\u30ec\u30f3\u88fd\u3001\u7c92\u5f8460\u03bcm\u4ee5\u4e0b\uff09\u3068\u5e02\u8ca9\u990c\u3092\u6df7\u5408\u3057\u305f\u990c\u3092\u4f5c\u6210\u3057\u3001OECD\u306b\u304a\u3044\u3066\u6709\u5bb3\u7269\u8cea\u3092\u8a55\u4fa1\u3059\u308b\u30e2\u30c7\u30eb\u751f\u7269\u3068\u3057\u3066\u6307\u5b9a\u3055\u308c\u308b\u30e1\u30c0\u30ab\u306b\u4e0e\u3048\u307e\u3057\u305f\u3002\u74b0\u5883\u4e2d\u3067\u8003\u3048\u3089\u308c\u308b\u66dd\u9732\u91cf\u3067\u6442\u53d6\u3055\u305b\u305f\u8a66\u9a13\u7fa4\u3068\u3001\u5e02\u8ca9\u990c\u306e\u307f\u3067\u98fc\u80b2\u3057\u305f\u5bfe\u7167\u7fa4\u309212\u9031\u9593\u89b3\u5bdf\u3057\u3001\u305d\u306e\u671f\u9593\u306e\u30e1\u30c0\u30ab\u306e\u6210\u9577\u7387\u3001\u7523\u5375\u6570\u3001\u53d7\u7cbe\u5375\u306e\u5b75\u5316\u7387\u3092\u6bd4\u8f03\u3057\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u7d4c\u53e3\u66dd\u9732\u3055\u308c\u305fMP\u30d3\u30fc\u30ba\u306e\u6d88\u5316\u7ba1\u306b\u304a\u3051\u308b\u6ede\u7559\u6642\u9593\u3092\u8abf\u3079\u307e\u3057\u305f\u3002<br \/>\r\n\u3000\u305d\u306e\u7d50\u679c\u3001MP\u30d3\u30fc\u30ba\u306f\u6700\u4f4e\u3067\u30824\u65e5\u3001\u6700\u59279\u65e5\u9593\u6d88\u5316\u7ba1\u306b\u6ede\u7559\u3059\u308b\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3057\u305f\uff08\u56f3\u4e2d\u306eb\uff09\u3002\u4e00\u822c\u306b\u5c0f\u578b\u9b5a\u985e\u3067\u306f\u3001\u4e0d\u6d88\u5316\u7269\u306f\u7d4c\u53e3\u6442\u53d6\u5f8c4\u6642\u9593\u4ee5\u5185\u306b\u6392\u6cc4\u3055\u308c\u307e\u3059\u3002\u3064\u307e\u308a\u3001MP\u30d3\u30fc\u30ba\u306f\u6d88\u5316\u7ba1\u306b\u304b\u306a\u308a\u9577\u6642\u9593\u6ede\u7559\u3057\u305f\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002\u5e02\u8ca9\u990c\u3068MP\u30d3\u30fc\u30ba\u3092\u5747\u4e00\u306b\u6df7\u5408\u3057\u305f\u990c\u3092\u4e0e\u3048\u307e\u3057\u305f\u304c\uff08\u56f3\u4e2d\u306ea\uff09\u3001\u30d5\u30f3\u3092\u898b\u308b\u3068MP\u30d3\u30fc\u30ba\u3068\u98df\u7269\u7531\u6765\u7269\u304c\u5206\u96e2\u3057\u3066\u3044\u307e\u3057\u305f\uff08\u56f3\u4e2d\u306ec\uff09\u3002\u3064\u307e\u308a\u3001MP\u30d3\u30fc\u30ba\u306f\u4e00\u5b9a\u306e\u584a\u306b\u306a\u308b\u307e\u3067\u6d88\u5316\u7ba1\u306b\u7559\u307e\u308a\u3001\u305d\u306e\u5f8c\u6392\u51fa\u3055\u308c\u305f\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002\u8a66\u9a13\u7fa4\u306e\u6210\u9577\u7387\u306f\u304a\u3088\u305d10%\u3001\u7523\u5375\u6570\u306f\u304a\u3088\u305d50%\u6e1b\u5c11\u3057\u307e\u3057\u305f\u3002\u3053\u308c\u306f\u6d88\u5316\u7ba1\u5185\u3067\u6ede\u7559\u3057\u305fMP\u30d3\u30fc\u30ba\u306b\u3088\u308b\u6804\u990a\u5438\u53ce\u963b\u5bb3\u304c\u4e00\u56e0\u3067\u306f\u306a\u3044\u304b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u307e\u305f\u3001\u8a66\u9a13\u7fa4\u304b\u3089\u5f97\u3089\u308c\u305f\u53d7\u7cbe\u5375\u306e\u5b75\u5316\u7387\u3082\u304a\u3088\u305d30%\u6e1b\u5c11\u3057\u3066\u3044\u307e\u3057\u305f\u3002\u73fe\u5728\u306e\u3068\u3053\u308d\u3001\u751f\u6b96\u529b\u304c\u4f4e\u4e0b\u3057\u305f\u7406\u7531\u306f\u4e0d\u660e\u3067\u3042\u308a\u3001\u6b21\u306e\u5b9f\u9a13\u3092\u9032\u3081\u3066\u3044\u307e\u3059\u3002<br \/>\r\n\u3000\u4eca\u56de\u306e\u7814\u7a76\u6210\u679c\u306b\u5f15\u304d\u7d9a\u304d\u3001\u69d8\u3005\u306a\u6fc3\u5ea6\u306eMP\u30d3\u30fc\u30ba\u3067\u306e\u66dd\u9732\u8a66\u9a13\u3092\u9032\u3081\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u5b9f\u9a13\u810a\u690e\u52d5\u7269\u3067\u306eNOAEL\uff08\u7121\u6bd2\u6027\u91cf\uff09\u3084 LOAEL\uff08\u6700\u5c0f\u6bd2\u6027\u91cf\uff09\u3092\u63d0\u793a\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u6bd2\u6027\u30c7\u30fc\u30bf\u3092\u84c4\u7a4d\u3057\u3066\u3044\u304f\u3053\u3068\u3067\u3001\u4ed6\u306e\u751f\u7269\u3084\u30d2\u30c8\u3078\u306e\u5916\u633f\u53ef\u80fd\u6027\uff08\u5b9f\u9a13\u52d5\u7269\u3067\u5f97\u3089\u308c\u305f\u7d50\u679c\u304b\u3089\u30d2\u30c8\u306a\u3069\u306e\u4ed6\u306e\u751f\u7269\u3078\u306e\u5f71\u97ff\u3092\u63a8\u5b9a\u3059\u308b\u3053\u3068\u306e\u53ef\u80fd\u6027\uff09\u304c\u9ad8\u307e\u308a\u3001\u516c\u8846\u885b\u751f\u4e0a\u306e\u57fa\u6e96\u3084\u5236\u9650\u3092\u8a2d\u5b9a\u3059\u308b\u969b\u306e\u508d\u8a3c\u3068\u3057\u3066\u306e\u6d3b\u7528\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\r\n\r\n\r\n<figure id=\"Fig.1\" class=\"fig1\">\r\n<a href=\"http:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/2019\/10\/21\/fig1.jpg\" target=\"_blank\" rel=\"noopener\"><img decoding=\"async\" src=\"\/univ\/faculty\/medicine\/uploads\/assets\/2019\/10\/21\/fig1.jpg\" width=\"600\" vspace=\"20\" alt=\"\u56f31\" border=\"0\"><\/a>\r\n\r\n<\/figure>\r\n\r\n<br \/ class=\"fig0\">\r\n\r\n<h5>\u63b2\u8f09\u8ad6\u6587<\/h5>\r\n\r\n<table class=\"citation\">\r\n <tr>\r\n  <td width=93>\u767a\u8868\u96d1\u8a8c\uff1a<\/td><td width=560>Environmental Pollution<\/td>\r\n <\/tr>\r\n<tr>\r\n  <td>\u8ad6\u6587\u30bf\u30a4\u30c8\u30eb\uff1a<\/td><td><a href=\"http:\/\/doi.org\/10.1016\/j.envpol.2019.113094\" target=\"_blank\" rel=\"noopener\">Ingestion of polyethylene microbeads affects the growth and reproduction of medaka, Oryzias latipes<\/a><\/td>\r\n <\/tr>\r\n <tr>\r\n  <td>\u7b46\u3000\u8005\uff1a<\/td><td>Shinichi Chisada, Masao Yoshida, Kanae Karita<br \/>\uff08\u82e3\u7530\u614e\u4e00\u3001\u5409\u7530\u6b63\u96c4\u3001\u82c5\u7530\u9999\u82d7\uff09\r\n<\/td>\r\n <\/tr>\r\n <tr>\r\n  <td>DOI:<\/td>  <td>10.1016\/j.envpol.2019.113094<\/td>\r\n <\/tr>\r\n<\/table>\r\n<br \/>\r\n<div>\r\n<p>\u885b\u751f\u5b66\u516c\u8846\u885b\u751f\u5b66\u5b66\u6559\u5ba4\u306e\u8a73\u7d30\u306f<a href=\"http:\/\/www.kyorin-u.ac.jp\/univ\/faculty\/medicine\/education\/labo\/hygienics\/\" target=\"_blank\" rel=\"noopener\">\u3053\u3061\u3089<\/a>\u3092\u3054\u89a7\u4e0b\u3055\u3044\u3002\r\n<p>\u885b\u751f\u5b66\u516c\u8846\u885b\u751f\u5b66\u5b66\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306e\u8a73\u7d30\u306f<a href=\"http:\/\/www.kyorin-u.ac.jp\/univ\/graduate\/medicine\/education\/departments\/mol-predictive-med\/#group2\" target=\"_blank\" rel=\"noopener\">\u3053\u3061\u3089<\/a>\u3092\u3054\u89a7\u4e0b\u3055\u3044\u3002\r\n<\/div>\r\n<br \/>\r\n<h5>\u554f\u3044\u5408\u308f\u305b\u5148<\/h5>\r\n<p class=\"noIndmt10\">\u674f\u6797\u5b66\u5712\u5e83\u5831\u5ba4<br \/>\r\n\u3000\u3000\u5e83\u5831\u5ba4\u3078\u306e\u304a\u554f\u3044\u5408\u308f\u305b\u306f<a href=\"https:\/\/www.kyorin-u.ac.jp\/univ\/contact\/\">\u3053\u3061\u3089<\/a>\u307e\u3067<br \/>\r\n<\/p>","protected":false},"excerpt":{"rendered":"<p>\u82e3\u7530\u3000\u614e\u4e00\u3000\uff08\u885b\u751f\u5b66\u516c\u8846\u885b\u751f\u5b66\u6559\u5ba4\u3000\u52a9\u6559\uff09\u3000 \u5409\u7530\u3000\u6b63\u96c4\u3000\uff08\u885b\u751f\u5b66\u516c\u8846\u885b\u751f\u5b66\u6559\u5ba4\u3000\u51c6\u6559\u6388\uff09 \u82c5\u7530\u3000\u9999\u82d7\u3000\uff08\u885b\u751f\u5b66\u516c\u8846\u885b\u751f\u5b66\u6559\u5ba4\u3000\u6559\u6388\uff09\u3000 \u7814\u7a76\u306e\u30cf\u30a4\u30e9\u30a4\u30c8 \u6c34\u57df\u74b0\u5883\u4e2d\u3067\u66dd\u9732\u3055\u308c\u5f97\u308b\u91cf\u306e\u30de\u30a4\u30af\u30ed\u30d7\u30e9\u30b9\u30c1\u30c3\u30af\u30d3\u30fc\u30ba\uff08\u30dd\u30ea\u30a8\u30c1 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