{"id":472,"date":"2026-04-01T09:00:49","date_gmt":"2026-04-01T00:00:49","guid":{"rendered":"http:\/\/www.kyorin-u.ac.jp\/univ\/user\/medicine\/fcm\/wordpress\/?page_id=472"},"modified":"2026-04-03T17:58:32","modified_gmt":"2026-04-03T08:58:32","slug":"staff","status":"publish","type":"page","link":"https:\/\/www.kyorin-u.ac.jp\/univ\/user\/medicine\/fcm\/staff","title":{"rendered":"\u5c02\u4efb\u6559\u54e1"},"content":{"rendered":"
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\u90e8\u9580\u9577\u30fb\u6559\u6388<\/h1>\n<\/div>\n<\/div>\n
\n\n\n\n
\"\"<\/td>\n\n

\u5927\u5c71\u3000\u5b66<\/h1>\n

Manabu OHYAMA M.D., Ph.D.<\/h2>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

<\/h4>\n

\u7565\u6b74<\/h4>\n

\u65e5\u672c\u76ae\u819a\u79d1\u5b66\u4f1a\u8a8d\u5b9a\u76ae\u819a\u79d1\u5c02\u9580\u533b\u3001\u65e5\u672c\u518d\u751f\u533b\u7642\u5b66\u4f1a\u518d\u751f\u533b\u7642\u8a8d\u5b9a\u533b<\/p>\n

1993\u5e742\u6708\u3000\u6176\u61c9\u7fa9\u587e\u5927\u5b66\u533b\u5b66\u90e8\u5352\u696d
\n1993\u5e744\u6708\u3000\u6176\u61c9\u7fa9\u587e\u5927\u5b66\u52a9\u624b\uff08\u533b\u5b66\u90e8\u89e3\u5256\u5b66\uff09
\n1994\u5e745\u6708\u3000\u6176\u61c9\u7fa9\u587e\u5927\u5b66\u533b\u5b66\u90e8\u7814\u4fee\u533b\uff08\u76ae\u819a\u79d1\uff09
\n1996\u5e747\u6708\u3000\u56fd\u7acb\u971e\u30f6\u6d66\u75c5\u9662\u76ae\u819a\u79d1\u30ec\u30b8\u30c7\u30f3\u30c8
\n1998\u5e744\u6708\u3000\u6176\u61c9\u7fa9\u587e\u5927\u5b66\u52a9\u624b\uff08\u533b\u5b66\u90e8\u76ae\u819a\u79d1\u5b66\uff09
\n2000\u5e747\u6708\u3000\u6771\u4eac\u96fb\u529b\u75c5\u9662\u76ae\u819a\u79d1\u526f\u79d1\u9577
\n2002\u5e747\u6708\u3000\u7c73\u56fdNIH\u3001National Cancer Institute\u76ae\u819a\u79d1\u8a2a\u554f\u7814\u7a76\u54e1
\n2005\u5e747\u6708\u3000\u6176\u61c9\u7fa9\u587e\u5927\u5b66\u52a9\u624b\uff08\u533b\u5b66\u90e8\u76ae\u819a\u79d1\u5b66\uff09
\n2006\u5e744\u6708\u3000\u6176\u61c9\u7fa9\u587e\u5927\u5b66\u5c02\u4efb\u8b1b\u5e2b\uff08\u533b\u5b66\u90e8\u76ae\u819a\u79d1\u5b66\uff09
\n2014\u5e744\u6708\u3000\u6176\u61c9\u7fa9\u587e\u5927\u5b66\u51c6\u6559\u6388\uff08\u533b\u5b66\u90e8\u76ae\u819a\u79d1\u5b66\uff09
\n2015\u5e744\u6708\u3000\u674f\u6797\u5927\u5b66\u6559\u6388\u533b\u5b66\u90e8\u76ae\u819a\u79d1\u5b66\u6559\u5ba4\u6559\u6388
\n2016\u5e744\u6708\u3000\u5927\u5b66\u9662\u533b\u5b66\u7814\u7a76\u79d1\u5171\u540c\u7814\u7a76\u65bd\u8a2d\u30d5\u30ed\u30fc\u30b5\u30a4\u30c8\u30e1\u30c8\u30ea\u30fc\u90e8\u9580\u90e8\u9580\u9577<\/p>\n

\u5c02\u9580\u5206\u91ce<\/h4>\n

\u30fb\u6bdb\u9aea\u75be\u60a3
\n\u30fb\u81ea\u5df1\u514d\u75ab\u6027\u75be\u60a3
\n\u30fb\u518d\u751f\u533b\u5b66
\n\u30fb\u5e79\u7d30\u80de\u751f\u7269\u5b66<\/p>\n

\u4e3b\u306a\u696d\u7e3e<\/h4>\n

1. Takahashi R, Kinoshita-Ise M, Yamazaki Y, Fukuyama M, Ohyama M. * Increase in CD8+ effector memory T cells re-expressing CD45RA correlates with intractability of severe alopecia areata. J Invest Dermatol ahead of print<\/p>\n

2. Harada K#, Ohyama M# (#; equal contribution), Niiyama S#, Irisawa R, Mae K, Mori M, Wakimoto H, Kinoshita-Ise M, Fukuyama M, Hayakawa R, Takagi M, Yamazaki M, Miyoshi M, Nishiyama S, Sato S, Nakazawa Y, Sugimoto T, Ogo M, Tsuboi R. When to expect scalp hair regrowth during treatment of severe alopecia areata with baricitinib: insights from trajectories analyses of patients enrolled in two phase III trials. J Dermatol 50(10): 1264-1254 (2023.12)<\/p>\n

3. Takagi M, Kinoshita-Ise M, Fukuyama M, Aoki S, Nishikawa S, Miyoshi M, Sugimoto T, Yamazaki M, Ogo M, Ohyama M.* A modified Sobel filter-based automated numerical algorithm enables immediate trichoscopic assessment of hair diameter diversity in male and female pattern hair loss. J Dermatol Sci 20:S0923-1811(23)00242-6 (2023.11)<\/p>\n

4. Ohyama M*, Kamei K, Yuasa A, Anderson P, Milligan G, Sakaki-Yumoto M. Economic burden of alopecia areata: A study of direct and indirect effect cost in Japan using real-world data. J Dermatol 50(10): 1264-1254 (2023.10)<\/p>\n

5. Shimoda-Komatsu Y, Yamazaki Y, Kimishima M, Mizukawa Y, Ohayma M.* Clinicopathological digital image analyses before and after thermal stimulation subdivide acquired idiopathic generalized anhidrosis into inflammatory and non- inflammatory type J Dermatol Sci 108(1): 12-21 (2022.10)<\/p>\n

6. King B, Ohyama M, Kwon O, Zlotogorski A, Ko J, Mesinkovska NA, Hordinsky M, Dutronc Y, Wu WS, McCollam J, Chiasserini C, Yu G, Stanley S, Holzwarth K, DeLozier AM, Sinclair R; BRAVE-AA Investigators. Two Phase 3 Trials of Baricitinib for Alopecia Areata. N Engl J Med 386(18): 1687-1699. (2022.5)<\/p>\n

7. Fukuyama M, Tsukashima A, Kimishima M, Yamazaki Y, Okano H, Ohyama M.<\/p>\n

Human iPS Cell-Derived Cell Aggregates Exhibited Dermal Papilla Cell Properties in in vitro Three-Dimensional Assemblage Mimicking Hair Follicle Structures. Front Cell Dev Biol. 2021 2;9:590333. (2021.8)<\/p>\n

8. Kinoshita-Ise M*, Ohyama M*, Ramjist JM, Foster SF, Yang VXD, Sachdeva M, Sade S, Shear NH. Ultra high-frequency ultrasound with seventy-MHz transducer in hair disorders: Development of a novel noninvasive diagnostic methodology J Dermatol Sci, 102(3):167-176. (2021.6)<\/p>\n

9. Shimoda-Komatsu Y, Yamazaki Y, Kimishima M, Tsukashima A, Ohyama M.* Digital-immunohistological dissection of immune privilege collapse in syringotropic autoimmune diseases: an implication for the pathogenesis. J Dermal Sci : 101(1) 30-39 (2021.1)<\/p>\n

10. Takahashi R, Sato Y, Kimishima M, Shiohara T, Ohyama M.* Intracellular accumulation of PD-1 molecules in circulating T lymphocytes in advanced malignant melanoma: an implication for immune evasion mechanism. Int J Clin Oncol 25(10):1861-1869 (2020.10\uff09<\/p>\n

\u53d7\u8cde\u5b66\u8853\u8cde<\/h4>\n

2002\u5e74 \u5e73\u621013\u5e74\u5ea6\u4e0a\u539f\u8a18\u5ff5\u751f\u547d\u79d1\u5b66\u8ca1\u56e3\u6d77\u5916\u7559\u5b66\u52a9\u6210\u91d1
\n\uff08\u30ea\u30b5\u30fc\u30c1\u30d5\u30a7\u30ed\u30fc\u30b7\u30c3\u30d7\uff09
\n2006\u5e74 William J. Cunliffe Scientific Award
\n\uff08the European Academy of Dermatology and Venereology\uff09
\n2008\u5e74 \u65e5\u672c\u7814\u7a76\u76ae\u819a\u79d1\u5b66\u4f1a\u30d5\u30a7\u30ed\u30fc\u30b7\u30c3\u30d7\u8cc7\u751f\u5802\u8cde<\/p>\n

\u6240\u5c5e\u5b66\u4f1a<\/h4>\n

\u30fb\u65e5\u672c\u76ae\u819a\u79d1\u5b66\u4f1a\uff08\u7406\u4e8b\uff09
\n\u30fb\u65e5\u672c\u7814\u7a76\u76ae\u819a\u79d1\u5b66\u4f1a\uff08\u7406\u4e8b\u9577\uff09
\n\u30fb\u6bdb\u9aea\u79d1\u5b66\u7814\u7a76\u4f1a\uff08\u4ee3\u8868\u4e16\u8a71\u4eba\uff09
\n\u30fb\u65e5\u672c\u81e8\u5e8a\u6bdb\u9aea\u5b66\u4f1a\uff08\u9867\u554f\uff09
\n\u30fb\u65e5\u672c\u4e7e\u766c\u5b66\u4f1a\uff08\u8a55\u8b70\u54e1\uff09
\n\u30fb\u65e5\u672c\u76ae\u819a\u60aa\u6027\u816b\u760d\u5b66\u4f1a\uff08\u4ee3\u8b70\u54e1\uff09
\n\u30fb\u65e5\u672c\u76ae\u819a\u514d\u75ab\u30a2\u30ec\u30eb\u30ae\u30fc\u5b66\u4f1a\uff08\u4ee3\u8b70\u54e1\uff09
\n\u30fb\u76ae\u819a\u304b\u305f\u3061\u7814\u7a76\u5b66\u4f1a\uff08\u7406\u4e8b\uff09
\n\u30fb\u65e5\u672c\u9999\u7ca7\u54c1\u5b66\u4f1a\uff08\u8a55\u8b70\u54e1\uff09
\n\u30fb\u65e5\u672c\u518d\u751f\u533b\u7642\u5b66\u4f1a\uff08\u8a8d\u5b9a\u533b\uff09
\n\u30fbThe Society for Investigative Dermatology
\n\u30fbEuropean Society for Investigative Dermatology
\n\u30fbAmerican Hair Research Society
\n\u30fb\u65e5\u672c\u30b5\u30a4\u30c8\u30e1\u30c8\u30ea\u30fc\u5b66\u4f1a
\n\u30fb\u65e5\u672c\u708e\u75c7\u30fb\u518d\u751f\u533b\u5b66\u4f1a
\n\u30fb\u65e5\u672c\u81e8\u5e8a\u76ae\u819a\u79d1\u533b\u4f1a<\/p>\n

\u5b66\u4f1a\u6d3b\u52d5<\/h4>\n

\u30fb\u6176\u61c9\u7fa9\u587e\u5927\u5b66\u975e\u5e38\u52e4\u8b1b\u5e2b\uff08\u533b\u5b66\u90e8\u76ae\u819a\u79d1\u5b66\uff09
\n\u30fbNPO\u6cd5\u4eba\u5186\u5f62\u8131\u6bdb\u75c7\u306e\u60a3\u8005\u4f1a\uff08\u7406\u4e8b\uff09
\n\u30fbBritish Journal of Dermatology (Specialist Associate Editor)
\n\u30fbAnnals of Dermatology(Editorial Board)
\n\u30fbExperimental Dermatology (Editorial Board)
\n\u30fbJournal of Dermatology (Editor)
\n\u30fb\u81e8\u5e8a\u76ae\u819a\u79d1\uff08\u7de8\u96c6\u4eba\uff09
\n\u30fbMonthly Book Derma\uff08\u7de8\u96c6\u4e3b\u5e79\uff09
\n\u30fbVisual Dermatology\uff08\u7de8\u96c6\u5354\u529b\u8005\uff09<\/p>\n

\n<\/div>\n
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\u526f\u90e8\u9580\u9577\u30fb \u51c6\u6559\u6388\u30fbWebMaster<\/h1>\n<\/div>\n<\/div>\n<\/div>\n
\n\n\n\n
\"\"<\/td>\n\n

\u9ad8\u6a4b\u3000\u826f<\/h1>\n

Ryo TAKAHASHI M.T., Ph.D.<\/h2>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u8b1b\u6f14\u4f9d\u983c\u306f\u3053\u3061\u3089\u304b\u3089\u304a\u554f\u3044\u5408\u308f\u305b\u304f\u3060\u3055\u3044\u3000\u2192\u3000\u304a\u554f\u3044\u5408\u308f\u305b<\/a><\/h4>\n

Academic Career<\/h3>\n

\u5b66\u4f4d\uff1a\u535a\u58eb(\u4fdd\u5065\u5b66)
\n\u56fd\u5bb6\u8cc7\u683c\uff1a\u81e8\u5e8a\u691c\u67fb\u6280\u5e2b<\/p>\n

1990\u5e74\uff08\u5e73\u62102\u5e74\uff09\u57fc\u7389\u770c\u7acb\u5742\u6238\u897f\u9ad8\u7b49\u5b66\u6821\u5352
\n1994\u5e74\uff08\u5e73\u62106\u5e74\uff09\u674f\u6797\u5927\u5b66 \u4fdd\u5065\u5b66\u90e8 \u81e8\u5e8a\u691c\u67fb\u6280\u8853\u5b66\u79d1\u5352
\n1994\u5e74\uff08\u5e73\u62106\u5e74\uff09\u7b2c40\u56de \u81e8\u5e8a\u691c\u67fb\u6280\u5e2b\u56fd\u5bb6\u8a66\u9a13\u5408\u683c, \u81e8\u5e8a\u691c\u67fb\u6280\u5e2b\u53d6\u5f97
\n1999\u5e74\uff08\u5e73\u621011\u5e74\uff09\u674f\u6797\u5927\u5b66 \u5927\u5b66\u9662 \u4fdd\u5065\u5b66\u7814\u7a76\u79d1 \u4fdd\u5065\u75c5\u7406\u5b66 \u535a\u58eb\u5f8c\u671f\u8ab2\u7a0b\u4fee\u4e86\u3002 \u535a\u58eb(\u4fdd\u5065\u5b66, \u674f\u6797\u5927\u5b66)<\/p>\n

\u5b66\u4f4d\u8ad6\u6587\u8981\u65e8\u304a\u3088\u3073\u5be9\u67fb\u8981\u65e8\uff1a\u300eIn vitro\u306b\u304a\u3051\u308b\u30d2\u30c8\u5de8\u6838\u7403\u30b3\u30ed\u30cb\u30fc\u5f62\u6210\u53ca\u3073\u5de8\u6838\u7403\u80de\u4f53\u7a81\u8d77\u5f62\u6210\u3078\u306e\u6297\u8840\u5c0f\u677f\u7cd6\u86cb\u767d\u30e2\u30ce\u30af\u30ed\u30fc\u30ca\u30eb\u6297\u4f53\u306e\u5f71\u97ff<\/a>\u300f\u3000\u56fd\u7acb\u56fd\u4f1a\u56f3\u66f8\u9928\uff1ahttps:\/\/ndlsearch.ndl.go.jp\/books\/R100000002-I000000332740#bib<\/a>\u3000\u4e3b\u8ad6\u6587\uff1aTakahashi R, Sekine N, and Nakatake\u00a0T: Influence of monoclonal antiplatelet glyco-protein antibodies on in\u00a0vitro human megakaryocyte colony formation and proplatelet formation. Blood, 93 (6): 1951-1958, 1999<\/a>, \u304a\u3088\u3073\u8868\u7d19<\/a>.<\/span><\/p>\n

1999\u5e74\uff08\u5e73\u621011\u5e74\uff09\u674f\u6797\u5927\u5b66 \u533b\u5b66\u90e8 \u52a9\u624b\uff08\u4efb\u671f\u5236\uff09
\n2000\u5e74\uff08\u5e73\u621012\u5e74\uff09\u674f\u6797\u5927\u5b66 \u533b\u5b66\u90e8 \u52a9\u624b
\n2007\u5e74\uff08\u5e73\u621019\u5e74\uff09\u674f\u6797\u5927\u5b66 \u533b\u5b66\u90e8 \u52a9\u6559
\n2014\u5e74\uff08\u5e73\u621026\u5e74\uff09\u674f\u6797\u5927\u5b66 \u533b\u5b66\u90e8 \u5b66\u5185\u8b1b\u5e2b
\n2015\u5e74\uff08\u5e73\u621027\u5e74\uff09\u674f\u6797\u5927\u5b66 \u533b\u5b66\u90e8 \u5c02\u4efb\u8b1b\u5e2b
\n2018\u5e74\uff08\u5e73\u621030\u5e74\uff09\u5927\u5b66\u9662\u533b\u5b66\u7814\u7a76\u79d1\u5171\u540c\u7814\u7a76\u65bd\u8a2d\u30d5\u30ed\u30fc\u30b5\u30a4\u30c8\u30e1\u30c8\u30ea\u30fc\u90e8\u9580\u526f\u90e8\u9580\u9577
\n2026\u5e74\uff08\u4ee4\u548c08\u5e74\uff09\u674f\u6797\u5927\u5b66 \u533b\u5b66\u90e8 \u51c6\u6559\u6388\u3002\u73fe\u5728\u306b\u81f3\u308b<\/p>\n

Research Areas<\/h3>\n

Works in immunology, dermatology, and oncology fields, especially focusing on T cell regulation, immune evasion mechanisms, and inflammatory\/autoimmune diseases such as alopecia areata, eczema herpeticum, and drug eruptions.<\/p>\n

Thematic Connections<\/h5>\n
\u2022Immune Regulation: From megakaryocytes \u2192 T cells \u2192 Tregs \u2192 effector memory T cells<\/div>\n
\u2022Pathological Focus: Drug eruptions \u2192 eczema \u2192 melanoma \u2192 alopecia areata<\/div>\n
\u2022Mechanistic Consistency: Dysfunctional immune regulation \u2192 disease severity\/resistance<\/div>\n

\u2022 \u91cd\u75c7\u5186\u5f62\u8131\u6bdb\u75c7\u306e\u75c5\u614b\u89e3\u660e
\n\u2022 \u91cd\u75c7\u85ac\u75b9\u306e\u75c5\u614b\u89e3\u660e<\/p>\n

\"Research<\/p>\n

1. Early Stage (1999 \u2013 2003)<\/h5>\n
\u2022Focus: Platelet biology, megakaryocyte development<\/div>\n
\u2022Key Paper: Blood (1999)<\/a> \u2192 role of monoclonal antiplatelet glycoprotein antibodies<\/div>\n
\u2022Transition into: T cell differentiation, skin-homing CD4 T cells (Journal of Immunology, 2003)<\/div>\n
<\/div>\n
2. Expansion into Clinical Immunology (2009 \u2013 2014)<\/h5>\n
\u2022Focus: Regulatory T cell dysfunction in drug eruptions and eczema herpeticum<\/div>\n
\u2022Landmark: Journal of Immunology, 2009<\/a> \u2192 highly cited (347citations)<\/span><\/strong>, linking Treg dysfunction with severe drug eruptions<\/div>\n
\u2022Paper: Journal of Immunology, 2014<\/a> \u2192 pathological role of Tregs in eczema herpeticum<\/div>\n
<\/div>\n
3. Oncology & Immune Evasion (2020)<\/h5>\n
\u2022Focus: Immune checkpoint molecules (PD-1) in malignant melanoma<\/div>\n
\u2022Insight: PD-1 accumulation \u2192 mechanism of immune evasion<\/div>\n
\u2022Paper: International Journal of Clinical Oncology, 2020<\/a><\/div>\n
<\/div>\n
4. Autoimmune Dermatology (2021 \u2013 on going)<\/h5>\n
\u2022Focus: Alopecia areata (treatment resistance and immune mechanisms)<\/div>\n
\u20222021: Mycoplasma infection & Treg regulation \u2192 Paper: The Journal of Infectious Diseases<\/a><\/div>\n
\u20222024 \u2013 on going: Effector memory CD8+ T cells re-expressing CD45RA \u2192 correlates with severity & treatment resistance in alopecia areata<\/div>\n
\u2022Shows translation of immunology into dermatological autoimmune disease<\/div>\n
\u2022Landmark: Journal of Investigative Dermatology 2024<\/a><\/div>\n
\u2022Paper: Journal of Investigative Dermatology 2025<\/a><\/div>\n
\n

Key Publications<\/h3>\n

\u2192\u5168\u696d\u7e3e\u306f\u3053\u3061\u3089\u3092\u3054\u89a7\u4e0b\u3055\u3044\u3002<\/a><\/strong><\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n
\"\"<\/td>\nTakahashi R<\/b><\/strong>, Kinoshita-Ise M, Yamazaki Y, Fukuyama M, and Ohyama M:Predominance of CD27-PD-1- effector memory T cells re-expressing CD45RA characterizes treatment-resistant severe alopecia areata: Journal of Investigative Dermatology.\u00a0145: 3195-3199.e6. 2025<\/a><\/strong><\/p>\n

\u88ab\u5f15\u7528\u6570\uff1a2<\/span>\uff08via Google Scholar\uff09<\/span><\/span><\/td>\n<\/tr>\n

\"\"<\/a><\/td>\nTakahashi R<\/strong><\/b>, Kinoshita-Ise M, Yamazaki Y, Fukuyama M, and Ohyama M: Increase in CD8+ Effector Memory T Cells Re-Expressing CD45RA Correlates with Intractability of Severe Alopecia Areata: Journal of Investigative Dermatology 144: 1654-1657.E7. 2024.<\/a><\/strong><\/p>\n

\u88ab\u5f15\u7528\u6570\uff1a9<\/span><\/td>\n<\/tr>\n

\"\"<\/td>\nTakahashi R<\/b>, Shiohara T, and Mizukawa Y:\u00a0Monocyte-Independent and -Dependent Regulation of Regulatory T-Cell Development in Mycoplasma Infection:\u00a0The Journal of Infectious Diseases 223:1733-1742, 2021<\/strong><\/a>.<\/p>\n

\u88ab\u5f15\u7528\u6570\uff1a10<\/span><\/td>\n<\/tr>\n

\"\"<\/td>\nTakahashi R<\/strong>, Sato Y, Kimishima M, \u00a0Shiohara T, and Ohyama M:\u00a0Intracellular accumulation of PD-1 molecules in circulating T lymphocytes in advanced malignant melanoma: an implication for immune evasion mechanism.\u00a0Int J Clin Oncol (10):1861-1869:\u00a0doi: 10.1007\/s10147-020-01732-8, 2020.<\/a><\/strong><\/p>\n

\u88ab\u5f15\u7528\u6570\uff1a4<\/span><\/td>\n<\/tr>\n

\"\"<\/td>\nTakahashi R,<\/span> Sato Y, Kurata M,\u00a0Yamazaki Y,\u00a0Kimishima M, and Shiohara T: Pathological role of regulatory T cells in\u00a0the initiation and maintenance of eczema herpeticum lesions.\u3000The\u00a0 Journal of Immunology 192: 969-978. 2014.<\/a><\/span>
\n\u88ab\u5f15\u7528\u6570\uff1a24<\/span><\/td>\n<\/tr>\n
\"cover.gif\"<\/td>\nTakahashi R, <\/span>Kano Y ,Yamazaki Y,\u00a0Kimishima\u00a0M, Mizukawa Y, and Shiohara T: Defective regulatory T cells in patients\u00a0with severe drug eruptions: timing of the dysfunction is associated\u00a0with the pathological phenotype and outcome.\u00a0 The Journal of Immunology 182:8071-79, 2009. <\/a><\/span>
\n\u88ab\u5f15\u7528\u6570\uff1a347<\/span><\/span><\/td>\n<\/tr>\n
\"jimmunol_cover.jpg\"<\/td>\nTakahashi R, <\/span>Mizukawa Y, Yamazaki\u00a0Y,\u00a0Hayakawa K, Hayakawa J, Kudo A and Shiohara T:\u00a0 In Vitro\u00a0Differentiation from Naive to Mature E-Selectin Binding CD4 T Cells:\u00a0Acquisition of Skin-Homing Properties Occurs Independently of Cutaneous\u00a0Lymphocyte Antigen Expression. The Journal of Immunology, 171: 5769-5777, 2003.<\/a><\/span>
\n\u88ab\u5f15\u7528\u6570\uff1a26<\/span><\/span><\/td>\n<\/tr>\n
\"blood_cover.jpg\"<\/td>\nTakahashi R, <\/span>Sekine N, and Nakatake\u00a0T: Influence of monoclonal antiplatelet glyco-protein antibodies on in\u00a0vitro human megakaryocyte colony formation and proplatelet formation. Blood, 93 (6): 1951-1958, 1999<\/a><\/span>, \u304a\u3088\u3073\u8868\u7d19<\/a>.
\n\u88ab\u5f15\u7528\u6570\uff1a150<\/span><\/span><\/td>\n<\/tr>\n
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\u6b74\u4ee3\u90e8\u9580\u9577<\/h1>\n

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\u90e8\u9580\u9577\u30fb\u6559\u6388 \u5927\u5c71\u3000\u5b66 Manabu OHYAMA M.D., Ph.D. \u7565\u6b74 \u65e5\u672c\u76ae\u819a\u79d1\u5b66\u4f1a\u8a8d\u5b9a\u76ae\u819a\u79d1\u5c02\u9580\u533b\u3001\u65e5\u672c\u518d\u751f\u533b\u7642\u5b66\u4f1a\u518d\u751f\u533b\u7642\u8a8d\u5b9a\u533b 1993\u5e742\u6708\u3000\u6176\u61c9\u7fa9\u587e\u5927\u5b66\u533b\u5b66\u90e8\u5352\u696d 1993\u5e744\u6708\u3000\u6176\u61c9\u7fa9\u587e\u5927\u5b66\u52a9\u624b\uff08 […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":16,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-472","page","type-page","status-publish","hentry"],"yoast_head":"\n\u5c02\u4efb\u6559\u54e1 - \u674f\u6797\u5927\u5b66\u5927\u5b66\u9662\u533b\u5b66\u7814\u7a76\u79d1\u5171\u540c\u7814\u7a76\u65bd\u8a2d\u30d5\u30ed\u30fc\u30b5\u30a4\u30c8\u30e1\u30c8\u30ea\u30fc\u90e8\u9580<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.kyorin-u.ac.jp\/univ\/user\/medicine\/fcm\/staff\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u5c02\u4efb\u6559\u54e1 - 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