{"id":210,"date":"2014-04-03T18:41:23","date_gmt":"2014-04-03T09:41:23","guid":{"rendered":"http:\/\/www.kyorin-u.ac.jp\/univ\/user\/medicine\/fcm\/wordpress\/?p=210"},"modified":"2014-04-03T18:41:23","modified_gmt":"2014-04-03T09:41:23","slug":"2012%e5%b9%b4%e5%ba%a6%e6%a5%ad%e7%b8%be","status":"publish","type":"post","link":"https:\/\/www.kyorin-u.ac.jp\/univ\/user\/medicine\/fcm\/archives\/210","title":{"rendered":"2012\u5e74\u5ea6\u696d\u7e3e"},"content":{"rendered":"


\n\u3010\u8ad6\u3000\u6587\u3011
\n1.\tMizukawa Y, Horie C, Yamazaki Y, Shiohara T. Detection of varicella-zoster virus antigens in lesional skin of zosteriform lichen planus but not in that of linear lichen planus.\u3000Dermatology 2012;225(1):22-6.
\n2.\tUshigome Y, Kano Y, Hirahara K, Shiohara T. Human herpesvirus 6 reactivation in drug-induced hypersensitivity syndrome and DRESS validation score. Am J Med 2012;125(7):e9-10.
\n3.\tShiohara T, Kano Y, Takahashi R, Ishida T, Mizukawa Y. Drug-induced hypersensitivity syndrome: recent advances in the diagnosis, pathogenesis and management.\u3000Chem Immunol Allergy 2012;97:122-38.
\n4.\tShiohara T, Mizukawa Y. Fixed drug eruption: the dark side of activation of intraepidermal CD8+ T cells uniquely specialized to mediate protective immunity.\u3000Chem Immunol Allergy 2012;97:106-21.
\n5.\tShiohara T, Kano Y. Drug-induced hypersensitivity syndrome: recent advances in drug allergy. Expert Rev Dermatol 2012; 7: 539-547
\n6.\tHayakawa J, Mizukawa Y, Kurata M, Shiohara T. A syringotropic variant of cutaneous sarcoidosisi: Presentation of 3 cases exhibiting defective sweating responses. J Am Acad Dermatol 2013 Jan 29 Epub ahead of print
\n7.\tUshigome Y, Kano Y, Ishida T, Hirahara K, Shiohara T. Short- and long-term outcomes of 34 patients with drug-induced hypersensitivity syndrome in a single institution. J Am Acad Dermatol 2012 Nov 19 Epub ahead of print
\n8.\tHirahara K, Kano Y, Asano Y, Shiohara T. Osteonecrosis of the femoral head in a patient with Henoch-Schoenlein purpura and drug-induced hypersensitivity syndrome treated with corticosteroids. Acta Derm Venereol 2013; 93:85-86.
\n9.\tShiohara T. Fixed drug eruption. UpToDate 2013
\n10.\tIshih A, Nagata T, Kobayashi F: The course of a primary infection of Plasmodium yoelii 17XL in both 129S1 and IFN-\u03b3 receptor deficient mice. Parasitol Res, 111(2):593-600, 2012 Augst. doi: 10.1007\/s00436-012-2873-2. Epub 2012 Mar 6.
\n11.\tInoue S-I, Niikura M, Takeo S, Mineo S, Kawakami Y, Uchida A, Kamiya S, Kobayashi F: Enhancement of dendritic cell activation via CD40 ligand-expressing \u03b3\u03b4 T cells is responsible for protective immunity to Plasmodium parasites. Proc Natl Acad Sci U S A, 109(30):12129-12134, 2012 July 24. doi: 10.1073\/pnas.1204480109. Epub 2012 Jul 9.
\n12.\tKurita M1, Okazaki M2, Kaminishi-Tanikawa A1, Niikura M, Takushima A1, Harii K1 (1Dept. Plast. Surg., Kyorin Univ. Sch. Med., 2Dept. Plast. Reconst. Surg., Grad. Sch. Tokyo Med. Dent. Univ.): Differential expression of wound fibrotic factors between facial and trunk dermal fibroblasts. Connect Tissue Res, 53(5):349-354, 2012. Epub 2012 Jul 24.
\n13.\tIshih A, Kawakami C, Todoroki A, Hirai H, Ohori K, Kobayashi F: Outcome of primary lethal and non-lethal Plasmodium yoelii malaria infection in BALB\/c and IFN-\u03b3 receptor-deficient mice following chloroquine treatment. Parasitol Res, 112(2):773-780, 2013 Feb. doi: 10.1007\/s00436-012-3197-y. Epub 2012 Nov 21.
\n14.\tTanabe K, Mita M, Palacpac MNQ, Arisue N, Tougan T, Kawai S, Jombart T, Kobayashi F, Horii T: Within-population genetic diversity of Plasmodium falciparum vaccine candidate antigens reveals geographic distance from a Central sub-Saharan African origin. Vaccine, 31(9):1334-1339, 2013 Feb 18. doi: 10.1016\/j.vaccine.2012.12.039. Epub 2013 Jan 4.
\n15.\tNiikura M, Inoue S-I, Mineo S, Yamada Y, Kaneko I, Iwanaga S,Yuda M, Kobayashi F: Experimental cerebral malaria is suppressed by disruption of nucleoside transporter 1 but not purine nucleoside phosphorylase. Biochem Biophys Res Commun, 2013 Feb 10. doi:pii: S0006-291X(13)00227-1. 10.1016\/j.bbrc.2013.02.004. [Epub ahead of print]
\n\u2003
\n\u3010\u53e3\u3000\u6f14\u3011
\n1.\t\u9ad8\u6a4b\u3000\u826f, \u5869\u539f\u54f2\u592b: Google\u30ab\u30ec\u30f3\u30c0\u30fc\u3092\u5229\u7528\u3057\u305fFCM\u6a5f\u5668\u4e88\u7d04\u30b7\u30b9\u30c6\u30e0\u306e\u69cb\u7bc9\uff1a\u7b2c21\u56de\u65e5\u672c\u30b5\u30a4\u30c8\u30e1\u30c8\u30ea\u30fc\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff0c\u5927\u962a\uff0c\u5e73\u621023\u5e746\u670825\u65e5
\n2.\t\u9ad8\u6a4b\u3000\u826f, \u5869\u539f\u54f2\u592b: Evolving FACS Technology \u30b5\u30fc\u30d0\u30fc\u76e3\u8996\u30bd\u30d5\u30c8\u30a6\u30a7\u30a2\u3068\u6e29\u5ea6\u30ed\u30ac\u30fc\u3092\u7528\u3044\u305fFCM\u6a5f\u5668\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u30b7\u30b9\u30c6\u30e0\u306e\u958b\u767a\uff1a \u7b2c21\u56de\u65e5\u672c\u30b5\u30a4\u30c8\u30e1\u30c8\u30ea\u30fc\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff0c\u5927\u962a\uff0c\u5e73\u621023\u5e746\u670825\u65e5
\n3.\t\u4e95\u4e0a\u4fe1\u4e00, \u65b0\u5009\u3000\u4fdd, \u5cef\u5c3e\u677e\u4e00\u90ce, \u7af9\u5c3e\u3000\u6681, \u5c0f\u6797\u5bcc\u7f8e\u60e0\uff08\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0\uff09\uff1aCD40L\u767a\u73fe\u03b3\u03b4 T\u7d30\u80de\u3092\u4ecb\u3057\u305f\u6a39\u72b6\u7d30\u80de\u6d3b\u6027\u5316\u306b\u3088\u308b\u30de\u30e9\u30ea\u30a2\u539f\u866b\u611f\u67d3\u9632\u5fa1\u6a5f\u69cb. \u7b2c23\u56de\u65e5\u672c\u751f\u4f53\u9632\u5fa1\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a, \u6771\u4eac, \u5e73\u621024\u5e747\u67089-11\u65e5.
\n4.\tManabu Higaki, Hiroo Wada, Shin-ichiro Mikura, Tetsuo Yasutake, Masuo Nakamura, Mamoru Niikura, Fumie Kobayashi, Hiroshi Kamma, Shigeru Kamiya, Hajime Takizawa and Hajime Goto (Dep.Resp.Med.): Enhanced neutrophilic inflammation in IL-10 deficient mice exposed to cigarette smoke (via TNF-a regulation). European Respiratory Society in Vienna 2011, Vienna, September 1-5, 2012.
\n5.\t\u5cef\u5c3e\u677e\u4e00\u90ce, \u65b0\u5009\u3000\u4fdd, \u4e95\u4e0a\u4fe1\u4e00,\u9ed2\u7530\u96c5\u5f66, \u5c0f\u6797\u5bcc\u7f8e\u60e0\uff1a\u598a\u5a20\u4e2d\u306e\u30de\u30a6\u30b9\u30de\u30e9\u30ea\u30a2\u539f\u866b\u611f\u67d3\u306b\u3088\u308b\u809d\u6a5f\u80fd\u969c\u5bb3.Liver dysfunction in pregnant mice infected with rodent malaria parasites. \u7b2c53\u56de\u65e5\u672c\u71b1\u5e2f\u533b\u5b66\u4f1a\u5927\u4f1a, \u5e2f\u5e83, \u5e73\u621024\u5e749\u67085-6\u65e5.
\n6.\tShin-Ichi Inoue, Mamoru Niikura, Satoru Takeo, Shoichiro Mineo, Yasushi Kawakami, Akihiko Uchida, Shigeru Kamiya, Fumie Kobayashi: Enhancement of dendritic cell activation via CD40 ligand-expressing \u03b3\u03b4 T cells is responsible for protective immunity to Plasmodium berghei XAT.XVIII International Congress for Tropical Medicine and Malaria. Lio de Janeiro, September 23rd-27th, 2012.
\n7.\tShin-Ichi Inoue, Mamoru Niikura, Fumie Kobayashi: Enhancement of dendritic cell activation via CD40 ligand-expressing \u03b3\u03b4 T cells is responsible for protective immunity to Plasmodium parasites. \u7b2c41\u4f1a\u65e5\u672c\u514d\u75ab\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a, \u795e\u6238, \u5e73\u621024\u5e7412\u67085-7\u65e5.
\n8.\tRyo Takahashi and Tetsuo Shiohara1\u3000 (1Dept. of Dermatology):\u3000 Increased expression of PILR\u03b1 on patrolling monocytes sensing HSV is the mechanism by which HSV evades immune attack, The International Investigative Dermatology 2012, Okinawa, Dec 7-8, 2012.
\n9.\tYukiko Ushigome1, Ryo Takahashi, Tetsuo Shiohara1 (1Dept. of Dermatology):Preferential elimination of patrolling monocyte sensing herpesvirus in drug-induced hypersensitivity syndrome, The International Investigative Dermatology 2012, Okinawa, Dec 7-8, 2012.
\n10.\tMamoru Niikura, Shoichiro Mineo, Shin-ichi Inoue, Masahiko Kuroda, Fumie Kobayashi: Development of severe pathology in immunized pregnant mice challenged with lethal malaria parasites. The 6th Nagasaki Symposium on Tropical Emerging Infectious Diseases\/The 11th Nagasaki-Singapore Medical Symposium, Nagasaki, December 10th-12th, 2012.
\n11.\t\u4e95\u4e0a\u4fe1\u4e00, \u65b0\u5009\u3000\u4fdd, \u5cef\u5c3e\u677e\u4e00\u90ce,\u5c0f\u6797\u5bcc\u7f8e\u60e0\uff1a\u03b3\u03b4 T\u7d30\u80de\u306b\u3088\u308b\u30de\u30e9\u30ea\u30a2\u539f\u866b\u611f\u67d3\u9632\u5fa1\u6a5f\u69cb \u301cCD40 ligand\u767a\u73fe\u03b3\u03b4T\u7d30\u80de\u3092\u4ecb\u3057\u305f\u6a39\u72b6\u7d30\u80de\u6d3b\u6027\u5316\u301c\u3000Enhancement of dendritic cell activation via CD40 ligand-expressing \u03b3\u03b4 T cells is responsible for protective immunity to Plasmodium parasites.\u3000\u7b2c35\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a, \u798f\u5ca1, \u5e73\u621024\u5e7412\u670811-14\u65e5.
\n12.\t\u6a9c\u57a3\u5b661\u3001\u548c\u7530\u88d5\u96c41\u3001\u65b0\u5009\u4fdd2\u3001\u5b89\u6b66\u54f2\u751f1\u3001\u4e09\u5009\u771f\u4e00\u90ce1\u3001\u4e2d\u6751\u76ca\u592b1\u3001\u795e\u8c37\u83022\u3001\u83c5\u9593 \u535a3\u3001\u5c0f\u6797\u5bcc\u7f8e\u60752\u3001\u6edd\u6fa4\u59cb1\u3001\u5f8c\u85e4\u51431\uff081\u674f\u6797\u5927\u5b66\u533b\u5b66\u90e8\u547c\u5438\u5668\u5185\u79d1\u30012\u540c\u30fb\u611f\u67d3\u75c7\u5b66\u30013\u540c\u30fb\u75c5\u56e0\u75c5\u7406\u5b66\uff09\uff1a\u30bf\u30d0\u30b3\u304c\u60f9\u8d77\u3059\u308b\u80ba\u306e\u708e\u75c7\u3078\u306eIL-10\u306e\u6291\u5236\u7684\u5f71\u97ff,\u7b2c85\u56de\u65e5\u672c\u751f\u5316\u5b66\u4f1a,\u798f\u5ca1, \u5e73\u621024\u5e7412\u670814-16\u65e5\uff08\u767a\u886816\u65e5\uff09.
\n13.\tShin-Ichi Inoue, Mamoru Niikura, Shoichiro Mineo, Fumie Kobayashi: \u03b3\u03b4 T cells exert a bppstomg effect on dendritic cell responses to Plasmodium parasites. Keystone Symposia on Molecular and Cellular Biology, Malaria Meeting, New Orleans, January 20th-25th, 2013\uff08\u767a\u886822\u65e5\uff09.
\n14.\t\u65b0\u5009\u3000\u4fdd\uff0c\u5cef\u5c3e\u3000\u677e\u4e00\u90ce\uff0c\u4e95\u4e0a\u4fe1\u4e00\uff0c\u5c0f\u6797\u5bcc\u7f8e\u60e0\uff1a\u598a\u5a20\u30de\u30a6\u30b9\u306b\u304a\u3051\u308b\u30de\u30e9\u30ea\u30a2\u306e\u75c5\u614b\u91cd\u75c7\u5316\u306e\u89e3\u6790\uff0eDevelopment of severe pathology in pregnant mice during malaria \u7b2c6\u56de\u5bc4\u751f\u866b\u611f\u67d3\u514d\u75ab\u7814\u7a76\u4f1a, \u5927\u5206, \u5e73\u621025\u5e743\u67088\u65e5-9\u65e5\uff08\u767a\u88688\u65e5\uff09.
\n15.\t\u4e95\u4e0a\u4fe1\u4e00, \u65b0\u5009\u3000\u4fdd, \u5cef\u5c3e\u677e\u4e00\u90ce, \u5c0f\u6797\u5bcc\u7f8e\u60e0\uff1a\u30de\u30e9\u30ea\u30a2\u539f\u866b\u611f\u67d3\u306b\u5bfe\u3059\u308b\u03b3\u03b4 T\u7d30\u80de\u30b5\u30d6\u30bb\u30c3\u30c8\u306e\u89e3\u660e\u306b\u3080\u3051\u305f\u89e3\u6790. Characterization of \u03b3\u03b4 T cell subsets during Plasmodium berghei XAT infection. \u7b2c6\u56de\u5bc4\u751f\u866b\u611f\u67d3\u514d\u75ab\u7814\u7a76\u4f1a, \u5927\u5206, \u5e73\u621025\u5e743\u67088\u65e5-9\u65e5\uff08\u767a\u88688\u65e5\uff09.
\n16.\t\u4e95\u4e0a\u3000\u4fe1\u4e00\uff0c\u65b0\u5009\u3000\u4fdd\uff0c\u5cef\u5c3e\u3000\u677e\u4e00\u90ce\uff0c\u5ddd\u4e0a\u3000\u6cf0\uff0c\u5185\u7530\u3000\u660e\u5f66\uff0c\u5c0f\u6797\u3000\u5bcc\u7f8e\u60e0\uff1a\u30de\u30e9\u30ea\u30a2\u539f\u866b\u611f\u67d3\u9632\u5fa1\u306b\u304a\u3051\u308b\u03b3\u03b4T\u7d30\u80de\u306e\u6a5f\u80fd\u89e3\u6790. Functions of \u03b3\u03b4 T cells in protective immunity against Plasmodium berghei XAT infection. \u7b2c82\u56de\u65e5\u672c\u5bc4\u751f\u866b\u5b66\u4f1a\u5927\u4f1a, \u6771\u4eac, \u5e73\u621025\u5e743\u670829-31\u65e5\uff08\u767a\u886829\u65e5\uff09.
\n17.\tMamoru Niikura, Shin\u2013Ichi Inoue, Shoichirou Mineo, Fumie Kobayashi: Expression of OX40L is enhanced on macrophages through TLR2, TLR4 or TLR9 signaling during attenuated murine malaria parasite infection. \u7b2c82\u56de\u65e5\u672c\u5bc4\u751f\u866b\u5b66\u4f1a\u5927\u4f1a, \u6771\u4eac, \u5e73\u621025\u5e743\u670829-31\u65e5\uff08\u767a\u886829\u65e5\uff09.
\n18.\t\u91d1\u5b50\u3000\u660e\uff0c\u4e94\u5341\u68f2\u3000\u7406\u6075\uff0c\u6728\u6751\u3000\u653f\u7d99\uff0cChaves Lius Fernando, George Taleo, \u7af9\u5c3e\u3000\u6681\uff0c\u576a\u4e95\u656c\u6587\uff0c\u7530\u8fba\u548c\u88c4\uff0cAnders Bjorkman, Marita Troye-Blomberg, Chris Drakeley: \u30de\u30e9\u30ea\u30a2\u64b2\u6ec510\u5e74\u5f8c\u306e\u4e09\u65e5\u71b1\u30de\u30e9\u30ea\u30a2\u611f\u67d3\u306b\u5bfe\u3059\u308b\u514d\u75ab\u9632\u5fa1\uff0e\u7b2c82\u56de\u65e5\u672c\u5bc4\u751f\u866b\u5b66\u4f1a\u5927\u4f1a, \u6771\u4eac, \u5e73\u621025\u5e743\u670829-31\u65e5\uff08\u767a\u886829\u65e5\uff09\uff0e\u7b2c82\u56de\u65e5\u672c\u5bc4\u751f\u866b\u5b66\u4f1a\u5927\u4f1a, \u6771\u4eac, \u5e73\u621025\u5e743\u670829-31\u65e5\uff08\u767a\u886831\u65e5\uff09.<\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[3],"tags":[],"class_list":["post-210","post","type-post","status-publish","format-standard","hentry","category-archive"],"yoast_head":"\n2012\u5e74\u5ea6\u696d\u7e3e - \u674f\u6797\u5927\u5b66\u5927\u5b66\u9662\u533b\u5b66\u7814\u7a76\u79d1\u5171\u540c\u7814\u7a76\u65bd\u8a2d\u30d5\u30ed\u30fc\u30b5\u30a4\u30c8\u30e1\u30c8\u30ea\u30fc\u90e8\u9580<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.kyorin-u.ac.jp\/univ\/user\/medicine\/fcm\/archives\/210\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta 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