2005年度業績

論　文
1)高橋 良：特集 I リンパ球の動態とケモカイン・接着分子．皮膚へのリンパ球のホーミングとケモカイン・接着分子．臨床免疫　45巻：147〜152，2006．
2)高橋 良：bossa mac ジョブズのプレゼンに学べ！．MacPeople 12巻：99頁，2006．
3)Tetsuo Shiohara1, Yoshiko Mizukawa1, Ryo Takahashi, Jun Hayakawa1 & Kazuhito Hayakawa1 (1Department of Dermatology) ：T-cell dynamics of inflammatory skin diseases．Expert Review of Clinical Immunology 1：357-368，2005.
4)Kano Y, Teraki Y & Shiohara T (Department of Dermatology) : Dramatic improvement of psoriatic erythroderma after acute hepatitis: analysis of cytokine synthesis capability in peripheral blood T cells., Br J Dermatol (in press)
5)Ohno T1, Kobayashi F2, Nishimura M1 (1Div. Exp. Anim., Cent. Promotion of Med. Res. Educ., Grad. Schl. Med., Nagoya Univ. 2 Division of Tropical Diseases and Parasitology Department of Infectious Diseases) : Fas has a role in cerebral malaria, but not in proliferation or exclusion of the murine parasite in mice. Immunogenetics, 57, 293-296, 2005.
6)Kano Y, Seishima M, Shiohara T (Department of Dermatology) : Hypogammaglobulinemia as an early sign of drug-induced hypersensitivity syndrome. J Am Acad Dermatol in press
7)Kano Y, Hirahara K, Sakuma K, Shiohara T (Department of Dermatology) : Several herpesviruses can reactivate in a severe drug-induced multi-organ reaction in the same sequential order as in graft-versus-host disease. Br J Dermatol in press
8)Kano Y, Mitsuyama Y, Hirahara K, Shiohara T (Department of Dermatology) : Mycoplasma pneumoniae infection-induced erythema nodosum, anaphylactoid purpura and acute urticaria in three people in a single family. J Am Acad Dermatol in press
9)Shiohara T, Kano Y (Department of Dermatology) : Drug-induced hypersensitivity syndrome (DIHS) : A reaction induced by a complex interplay among herpesviruses and antiviral and antidrug immune responses. Allergol Int 2006;55:1-8.
10)Shiohara T, Mizukawa Y (Department of Dermatology) : The immunological basis of lichenoid tissue reaction. Autoimmunity Review 2005;4:236-241.
11)Shiohara T, KanoY (Department of Dermatology) : Are viral infections responsible for the development of drug-induced hypersensitivity syndrome as well as graft-versus-host diseases? Dermatology 2005;210:259-260.
12)水川良子 (皮膚科) ：TLRと皮膚炎. アレルギー科　20(3) ：268-272, 2005
単行本
1.高橋 良：Keynote 2プレゼンテーション入門—ビギナーからPowerPointユーザーまで．東京都，秀潤社，2005．
口　演
1)大崎敬子, 花輪智子, 蔵田 訓, 田口晴彦, 神谷 茂 (感染症学講座微生物) ：Helicobacter pylori luxS変異株の性状解析. 第78回 日本細菌学会総会, 東京, 平成17年4月4-6.
2)石井　明1, 鈴木　亨1, 永田　年2, 小林富美惠3, 寺田　護1 (1浜松医大・寄生虫学 , 2浜松医大・微生物学 , 2感染症学教室(寄生虫学部門) ：Plasmodium yoelii 17XL感染に対する野生型129とIFN-γRノックアウトマウスの感受性．第74回日本寄生虫学会大会, 米子, 平成17年４月9日．
3)谷口委代1, 小林富美惠2, 北　潔3, 小島莊明4，安保　徹1，渡部久実5(1新潟大院・医歯・免疫医動物 , 2感染症学教室(寄生虫学部門) , 3東大院・医・生物医化学，4ACIPAC・タイ，5琉球大・遺伝子実験センター・感染免疫制御) ：タイ国における熱帯熱マラリア患者血清中の抗核抗体とリンパ球サブセットの経時的変化．第74回日本寄生虫学会大会, 米子, 平成17年４月9日．
4)Fumie Kobayashi1, Maiko Shibata2, Yasushi Kawakami2, Akihiko Uchida2, Seiji Waki3, (1 Division of Tropical Diseases and Parasitology Department of Infectious Diseases, 2Lab. of Medical Zoology, Azabu Univ., 3Gunma Prefect. Coll. Hlth. Sci.) : Effect of CD4+CD25+ T cell depletion on cytokine and specific antibody production during the course of Plasmodium berghei blood-stage infection. 第74回日本寄生虫学会大会, 米子, 平成17年４月9日．
5)高橋 良, 水川良子1, 塩原哲夫1 (1皮膚科) ：ヒトCD4+Ｔ細胞のE-selectin ligand発現におけるFucT-4の補助的役割，第30回日本研究皮膚科学会年次学術大会 (プレナリー口演) ，横浜，平成17年4月20- 22日
6)Mizukawa Y1, Shiohara T1, Ra Chisei2 (1Department of Dermatology, 2Nihon University School of Medicine Department of Medicine) : IgE is key to regulating TLR-2-depending innate immune responses of mast cells. The 30th Annual Meeting of the Japanese Society for Investigative Dermatology, Yokohama, Apr. 20th, 2005.
7)Takahashi M1, Taguchi H2, Osaki T2, Kamiya S2 (1Miyarisan Pharmaceutical, 2Department of Infectious Disieases) ：The effect of probiotic bacterium Clostridium butyricum on Clostridium difficile infection. The XVth International Symposium on Gnotobiology, June. 20-24, 2005, Tokyo.
8)Kamiya S, Osaki T (Department of Infectious Disieases) ：Quorum sensing in Helicobacter pylori. The XVth International Symposium on Gnotobiology, June. 20-24, 2005, Tokyo.
9)満足 滝, 大崎敬子, 蔵田 訓, 田口晴彦, 神谷 茂 (感染症学講座微生物) ：Helicobacter pyloriの胃上皮細胞への付着性に及ぼす加工乳蛋白FP-10の効果. 第8回 日本臨床腸内微生物学会総会, 東京, 平成17年9月10日.
10)狩野葉子, 勝田倫江, 武林亮子, 寺木祐一, 塩原哲夫 (皮膚科学教室) : 薬剤性肝障害後に急激に軽快した乾癬性紅皮症—検査所見の検討を加えてー.　第20回日本乾癬学会 , 軽井沢 , 平成17年9月10日
11)Fumie Kobayashi1, Maiko Shibata2, Yasushi Kawakami2, Akihiko Uchida2, Seiji Waki3, Shigeru Kamiya1 (1 Division of Tropical Diseases and Parasitology Department of Infectious Diseases , 2Lab. of Medical Zoology, Azabu Univ., 3Gunma Prefect. Coll. Hlth. Sci.) : CD4+CD25+ T cells contribute to control of parasitemia in Plasmodium berghei XAT infection in mice. The World Congress on “Medicine and Health in the Tropics” that incorporates the XVIth International Congress for Tropical Medicine and Malaria of the International Federation of Tropical Medicine, the IVth European Congress of the Federation of the European Societies of Tropical Medecine and International Health and the VIIth International Congress of the “Société de Pathologie Exotique” (The French Society of Tropical Medicine) . Marseille, September 11th –15th , 2005.
12)Hisami Watanabe1, Fumie Kobayashi2, Varee Wongchotigul3, Kiyoshi Kita4, Sornchai Looareesuwan5 (1Div. of Cell. Mol. Immunol., Cent. of Mol. Biosci., Univ. of the Ryukyus; 2Division of Tropical Diseases and Parasitology Department of Infectious Diseases.; 3Dept. of Microbiol. Immunol., Fac. of Trop. Med., Mahidol Univ.; 4Dept. of International Biomed. Sci.; Grad. Schl. of Med., Univ. of Tokyo; 5Dept. of Clin. Trop. Med., Fac. of Trop. Med., Mahidol Univ.) : Analysis of natural killer T cell subsets in patients with severe and uncomplicated falciparum malaria in Thailand. The World Congress on “Medicine and Health in the Tropics” that incorporates the XVIth International Congress for Tropical Medicine and Malaria of the International Federation of Tropical Medicine, the IVth European Congress of the Federation of the European Societies of Tropical Medecine and International Health and the VIIth International Congress of the “Société de Pathologie Exotique” (The French Society of Tropical Medicine) . Marseille, September 11th –15th, 2005.
13)Ryo Takahashi, Yoshiko Mizukawa1, and Tetsuo Shiohara1 (1Department of Dermatology) ：Coordinate and Ssequential expression of fucosyltransferases, FucT-4 and FucT-7, regulates skin-homing CD4+ T cell differentiation. European Immunodermatology Society Satellite Meeting, Tubingen Germany, Sep 21 – 24, 2005.
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15)Mizukawa Y, Shiohara T (Department of Dermatology, ) : IgE is a negative regulator of toll-like receptor-2-dependent, immediate-type hypersensitivity reactions mediated by mast cells. 2005 ESDR meeting Tubingen, Sep. 23th, 2005.
16)満足 滝, 大崎敬子, 蔵田 訓, 田口晴彦, 神谷 茂 (感染症学講座微生物) ：Helicobacter pyloriの細胞付着性に対する加工乳蛋白FP-10の効果. 第88回 日本細菌学会関東支部総会, 浜松, 平成17年10月20-21.
17)水川良子 (皮膚科) ：アレルギー反応に関与する新しい細胞内伝達系　FcεRIとTLRのクロストーク. 第55回日本アレルギー学会秋季学術大会, 盛岡 , 平成17年10月２１日.
18)大崎敬子, 神谷 茂 (感染症学講座微生物) ：Helicobacter pyloriの持続感染成立におけるクオラムセンシングの役割解析. 第54回 日本感染症学会東日本地方会総会・第52回 日本化学療法学会東日本支部総会合同学会学術講演会, 東京, 平成17年10月27-28.
19)森井祐子1 , 山口博之1 , 小林富美恵2 , 山本容正1(1阪大院・医・生体情報科学・分子微生物学 , 2感染症学教室 (寄生虫学部門) ) ：自由生活性アメーバ内でのChlamydia pneumoniaeの生存能力に関して．第＠回日本細菌学会関西支部総会，神戸，平成17年10月29日
20)高橋 良：インターネットの最新トピックス，東京都臨床検査技師会　臨床検査情報システム研究班，東京 , 平成18年2月10日
21)Takako Osaki1, Tomoko Hanawa1, Taki Manzoku1, Haruhiko Taguchi1, Satoshi Kurata1, Xu Yen1, 2, and Shigeru Kamiya1 (1Department of Infectious Disieases, 2Department of Microbiology, Kunming Medical School, Kumming, Republic of China.) Mutation of luxS affects motility and infectivity of Helicobacter pylori in gastric mucosa of Mongolian gerbil model. The 5th Korea-Japan-China Joint Conference On Helicobacter Infection. Sanya, China, Feb. 17-19, 2006.
22)Ryo Takahashi, Yoshiko Mizukawa1, and Tetsuo Shiohara1 (1Department of Dermatology) ：Direct visualization of the expression of E-selectin ligands on human CD4 skin-homing T cells. Strategies for controlling emerging and reemerging infectious diseases in Southeast Asia in JSPS Core University Program, Bangkok Thailand, Mar 27, 2006.