【口　演】

1. Keino H1, Watanabe T1, Sato Y2, Niikura M3, Wada Y4, Okada AA1 （1Department of Ophthalmology, 2Division of Radioisotope Research, 3Laboratory of Animals, Kyorin Univerisity School of Medicine, 4Synta Pharmaceuticals Corporation, MA, USA）： Therapeutic effect of the potent IL-12/IL-23 inhibitor STA-5326 in experimental autoimmune uveoretinitis.  ARVO （Association for Research in Vision and Ophthalmology） Fort. Lauderdale FL, Apr. 2, 2008.
2. 新倉保1,2, 北潔2, 小林富美惠3（1杏林大・院・医・実験動物, 2東大・院・医・国際保健, 3杏林大・医・感染症）： マウスマラリア原虫弱毒株との複合感染はPlasmodium berghei NK65強毒株感染による肝傷害を抑制する. 第77回日本寄生虫学会大会, 長崎, 平成20年4月2-4日.
3. 田邊將信1，深尾太郎1，永田博司2，関塚永一3，宮崎耕司3，小林富美惠4，竹内勤1（1慶應大・医・熱帯寄生虫，２けいゆう病院・内科，3国立埼玉・内科, 4杏林大・感染症学）： 慢性マンソン住血吸虫感染マウスはPseudomonas aeruginosa 致死感染に対し抵抗性である．第77回日本寄生虫学会大会, 長崎, 平成20年4月4日.
4. 藤野隆志1, 松尾智英1, 今上絵理2, 小林富美惠1, 松井利博1（1杏林大・感染症学,2杏林大・保健学部）： Eimeria krijgsmanni感染マウスに対する数種サルファ剤の効果．第77回日本寄生虫学会大会, 長崎, 平成20年4月4日.
5. Ishii A1 and Kobayashi F2（1Dept. Inf. Dis., Hamamatsu Univ. Sch. Med., 2Dept. Inf. Dis., Kyorin Univ.）： Effects of chloroquine treatment on Plasmodium yoelii 17XL infection in IFN-gamma KO mice．第77回日本寄生虫学会大会, 長崎, 平成20年4月4日．
6. Shiohara T1, Kano Y1, Takahashi R （1 Department of Dermatology）：  Update on regulators：  regulatory T cells in DIHS/DRESS and SJS/TEN. 3rd International drug hypersensitivity meeting. Paris, Apr. 2, 2008.
7. Kano Y1, Hirahara K1, Asano Y1, Mitsuyama Y1, Takahashi R, Shiohara T1 （1 Department of Dermatology）：  Association between drug and human herpesvirus in drug-induced hypersensitivity syndrome/drug rash with eosinophilia and systemic symptoms. 3rd International drug hypersensitivity meeting, Paris, Apr. 2, 2008.
8. Takahashi R and Shiohara T1 （1Dept. of Dermatology）：  Trafficking receptor expression on regulatory t cells in severe drug eruptions, 3rd International drug hypersensitivity meeting, Paris, Apr. 11-13, 2008.
9. Mitsuyama Y1, Kano Y1, Hirahara K1, Mizukawa Y1, Shiohara T1 （1 Department of Dermatology）：  Usefulness of monitoring of cytokine expression to evaluate therapeutic efficacy of plasmapheresis in patients with toxic epidermal necrolysis. 3rd International drug hypersensitivity meeting, Paris, Apr. 2, 2008.
10. Takahashi R, Kimisima M1, Yamazaki Y1, and Shiohara T1 （1Dept. of Dermatology）：  Severe drug hypersensitivity disorders is induced by dysfunctional Tregs, The International Investigative Dermatology 2008, Kyoto, May. 14-17, 2008.
11. Aota N1, Fukuhara M1, Hirahara K1, Kano Y1, Shiohara T1 （1 Department of Dermatology）：  Autoimmune disease as sequelae of drug-induced hypersensitivity syndrome. 2nd International conference on cutaneous lupus erythematosus, Kyoto, May. 12, 2008.
12. Kano Y1, Asano Y1, Hirahara T1, Shiohara T1 （1 Department of Dermatology）：  Autoimmune diseases occurring after drug-induced hypersensitivity syndrome. 6th International conference on HHV-6 & 7, Baltimore, Jun. 21, 2008. 
13. 小林富美惠1 （1杏林大・感染症学）： マウスマラリアモデルの功罪： 第16回分子寄生虫ワークショップ,  群馬, 平成20年8月3-6日.
14. 新倉保1,2, 北潔2, 小林富美惠3（ 1杏林大・院・医・実験動物, 2東大・院・医・国際保健, 3杏林大・医・感染症） ： Plasmodium berghei ANKA強毒株感染によって引き起こされる脳マラリア様症状はマウスマラリア原虫弱毒株との複合感染によって抑制される. 第16回分子寄生虫ワークショップ, 群馬, 平成20年8月3-6日.
15. Mamoru Niikura1,3, Shigeru Kamiya　2, Kiyoshi Kita　3, Fumie Kobayashi　2 （1　Institute of Laboratory Animals, Graduate School of Medicine 2　Department of Infectious Diseases, Faculty of Medicine, Kyorin University, 3　Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo.） ： Liver injury caused by Plasmodium berghei NK65 is suppressed by coinfection with nonlethal murine malaria parasites. 16th Japanese-German Cooperative Symposium on Protozoan Diseases. Goettingen, Sep. 24-29, 2008.
16. Niikura M1,2, Kamiya S3, Kita K2 and Kobayashi F3 （1Inst. Lab. Anim., Kyorin Univ. Schl. Med., 2Dept. Biomed. Chem., Grad. Sch. Med., Univ of Tokyo, 3Dept. Inf. Dis., Kyorin Univ.）：  Liver injury caused by Plasmodium berghei NK65 is suppressed by coinfection with nonlethal murine malaria parasites. The 16th Japanese-German Cooperative Symposium on Protozoan Diseases. Goettingen, Sep. 24-29, 2008.
17. 新倉保1,2, 北潔2, 小林富美惠3 （ 1杏林大・院・医・実験動物, 2東大・院・医・国際保健, 3杏林大・医・感染症） ： マウスにおける脳マラリア様症状は弱毒株マラリア原虫との複合感染によって抑制される. 第7回分子寄生虫・マラリア研究フォーラム, 松山, 平成20年10月10-11日.
18. Niikura M1,2 and Kobayashi F3 （1Inst. Lab. Anim., Kyorin Univ. Schl. Med., 2Dept. Biomed. Chem., Grad. Sch. Med., Univ of Tokyo, 3Dept. Inf. Dis., Kyorin Univ.）：  IL-10 plays a crucial role for the suppression of experimental cerebral malaria by coinfection with nonlethal murine malaria parasites. The 38th Annual Meeting of Japanese Society of Immunologists, Kyoto, Dec. 1-3, 2008.
19. Mamoru Niikura1,2, Fumie Kobayashi3 （1Institute of Laboratory Animals, Graduate School of Medicine, Kyorin University, 2 Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, 3Department of Infectious Diseases, Faculty of Medicine, Kyorin University.） ： IL-10 plays a crucial role for the protection of experimental cerebral malaria by coinfection with nonlethal malaria parasites. 第38回日本免疫学会総会・学術集会, 京都, 平成20年12月1-3日.
20. Kobayashi F1, Niikura M2,3 and Kita K3 （1Dept. Inf. Dis., Kyorin Univ.,2Inst. Lab. Anim., Kyorin Univ., 3Dept. Biomed. Chem., Grad. Sch. Med., Univ of Tokyo）：  Supression of severe pathogenisis during coinfection with lethal and nonlethal mararia parasites：  A consideration of possible mechanisms by using murine malaria models. JSPS Seminar, 2009：  Strategies for controlling emerging and re-emerging infectious diseases in Southeast Asia in JSPS Core University Program, Tokyo, Jan. 20, 2009.
21. 新倉保1, 2，北潔1，小林富美惠3（１東大・院・医・生物医化学，２杏林大・院・医・実験動物, 3杏林大・感染症）： マウスマラリア原虫複合感染におけるIL-10の意義と役割． 第2回原虫感染免疫研究会,  佐賀市, 平成21年2月21-22日.
22. Mamoru Niikura1,2, Kiyoshi Kita2, Fumie Kobayashi3 （1Institute of Laboratory Animals, Graduate School of Medicine, Kyorin University, 2 Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, 3Department of Infectious Diseases, Faculty of Medicine, Kyorin University.） ： Coinfection with nonlethal malaria parasites suppresses experimental cerebral malaria in IL-10 dependent-manner. 第78回日本寄生虫学会大会, 東京, 平成21年3月27-28日.
23. Niikura M1,2, Kita K2, Kobayashi F3 （1Inst. Lab. Anim., Kyorin Univ., 2Dept. Biomed. Chem., Grad. Sch. Med., Univ of Tokyo, 3Dept. Inf. Dis., Kyorin Univ.）：  Coinfection with nonlethal malaria parasites suppresses experimental cerebral malaria in IL-10-dependent manner. 第２回日本寄生虫学会大会, 東京, 平成21年3月27-28日.

【論　文】

1. Keino H1, Watanabe T1, Sato Y2, Niikura M3, Wada Y4, Okada AA1 （1Department of Ophthalmology, 2Division of Radioisotope Research, 3Laboratory of Animals, Kyorin Univerisity School of Medicine, 4Synta Pharmaceuticals Corporation, MA, USA）： Therapeutic effect of the potent IL-12/IL-23 inhibitor STA-5326 in experimental autoimmune uveoretinitis.    Arthritis Res Ther 10： R122, 2008.
2. Shiohara T1, Mizukawa Y1, Takahashi R, Kano Y1 （1 Department of Dermatology）：  Pathomechanisms of lichen planus autoimmunity elicited by cross-reactive T cells. Curr Dir Autoimmun 10： 206-226, 2008.
3. Sirirat Amonpatumrat1,3, Hiroyuki Sakurai1, Pattama Wiriyasermkul12, Narakorn Khunweeraphong1,2, Shushi Nagamori2, Hidekazu Tanaka2, Pawinee Piyachaturawat3,4 and Yoshikatsu Kanai2 （1 Department of Pharmacology and Toxicology, Kyorin University School of Medicine, Japan, 2 Division of Bio-system Pharmacology, Department of Pharmacology, Graduate School of Medicine, Osaka University, Japan 3 Toxicology Graduate Program, Faculty of Science, Mahidol University, Thailand,4 Department of Physiology, Faculty of Science, Mahidol University, Thailand）： L-Glutamate Enhances Methylmercury Toxicity by Synergistically Increasing Oxidative Stress. J Pharmacol Sci  108： 280-289. 2008
4. Mamoru Niikura1,3, Shigeru Kamiya2, Kiyoshi Kita3, Fumie Kobayashi2 （1Institute of Laboratory Animals, Graduate School of Medicine 2Department of Infectious Diseases, Faculty of Medicine, Kyorin University, 3Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo.）：  Coinfection with nonlethal murine malaria parasites suppresses pathogenesis caused by Plasmodium berghei NK65. J Immunol 180：  6877-6884. 2008.
5. Hiroshi Keino1, Takayo Watanabe1, Yasuhiko Sato2, Mamoru Niikura3, Yumiko Wada4, and Annabelle A Okada1 （1Department of Ophthalmology, 2Division of Radioisotope Research, Faculty of Medicine,  3Laboratory of Animals, Graduate School of Medicine, Kyorin University, 4Synta Pharmaceuticals Corporation, 45 Hartwell Ave. Lexington, MA 02421, USA.） ： Therapeutic effect of a potent IL-12/IL-23 inhibitor STA-5326 on experimental autoimmune uveoretinitis. Arthritis Res Ther 10：R122,  2008.
6. Ishih A1, Nagata T1, Kobayashi F2, Muregi F.W1, Ohori K1, and Miyase T1（1Dept. Inf. Dis., Hamamatsu Univ. Sch. Med., 2Dept. Inf. Dis., Kyorin Univ.）：  Possible involvement of IFN-g in earlier mortality of Plasmodium berghei NK65-infected BALB/c mice after febrifugine treatment. Southeast Asian J Trop Med Public Health 39： 949-956, 2008.
7. Aota N1, Hirahara K1, Kano Y1, Fukuoka T1, Yamada A1, Shiohara T1 （1 Department of Dermatology）：  Systemic lupus erythematosus presenting with Kikuchi-Fujimoto’s disease as a long-term sequele of drug-induced hypersensitivity syndrome, a possible role of Epstein-Barr virus reactivation. Dermatology 218：275-7, 2009.

【著　書】

1. Shiohara T1, Mizukawa Y1, Takahashi R, Kano Y1 （1 Department of Dermatology）：  Pathomechanisms of lichen planus autoimmunity elicited by cross-reactive T cells. In：  Dermatologic Immunity. Nickoloff BJ, Nestle FO （Ed.） Basel, Karger, 2008. p. 206-226.

【その他】

1. 研究成果　高橋良：薬剤性過敏症症候群における制御性Ｔリンパ球の機能解析． 平成20年度科学研究費補助金 若手研究（B）研究代表者