2012年度業績

【論　文】
1. Mizukawa Y, Horie C, Yamazaki Y, Shiohara T. Detection of varicella-zoster virus antigens in lesional skin of zosteriform lichen planus but not in that of linear lichen planus.　Dermatology 2012;225(1):22-6.
2. Ushigome Y, Kano Y, Hirahara K, Shiohara T. Human herpesvirus 6 reactivation in drug-induced hypersensitivity syndrome and DRESS validation score. Am J Med 2012;125(7):e9-10.
3. Shiohara T, Kano Y, Takahashi R, Ishida T, Mizukawa Y. Drug-induced hypersensitivity syndrome: recent advances in the diagnosis, pathogenesis and management.　Chem Immunol Allergy 2012;97:122-38.
4. Shiohara T, Mizukawa Y. Fixed drug eruption: the dark side of activation of intraepidermal CD8+ T cells uniquely specialized to mediate protective immunity.　Chem Immunol Allergy 2012;97:106-21.
5. Shiohara T, Kano Y. Drug-induced hypersensitivity syndrome: recent advances in drug allergy. Expert Rev Dermatol 2012; 7: 539-547
6. Hayakawa J, Mizukawa Y, Kurata M, Shiohara T. A syringotropic variant of cutaneous sarcoidosisi: Presentation of 3 cases exhibiting defective sweating responses. J Am Acad Dermatol 2013 Jan 29 Epub ahead of print
7. Ushigome Y, Kano Y, Ishida T, Hirahara K, Shiohara T. Short- and long-term outcomes of 34 patients with drug-induced hypersensitivity syndrome in a single institution. J Am Acad Dermatol 2012 Nov 19 Epub ahead of print
8. Hirahara K, Kano Y, Asano Y, Shiohara T. Osteonecrosis of the femoral head in a patient with Henoch-Schoenlein purpura and drug-induced hypersensitivity syndrome treated with corticosteroids. Acta Derm Venereol 2013; 93:85-86.
9. Shiohara T. Fixed drug eruption. UpToDate 2013
10. Ishih A, Nagata T, Kobayashi F: The course of a primary infection of Plasmodium yoelii 17XL in both 129S1 and IFN-γ receptor deficient mice. Parasitol Res, 111(2):593-600, 2012 Augst. doi: 10.1007/s00436-012-2873-2. Epub 2012 Mar 6.
11. Inoue S-I, Niikura M, Takeo S, Mineo S, Kawakami Y, Uchida A, Kamiya S, Kobayashi F: Enhancement of dendritic cell activation via CD40 ligand-expressing γδ T cells is responsible for protective immunity to Plasmodium parasites. Proc Natl Acad Sci U S A, 109(30):12129-12134, 2012 July 24. doi: 10.1073/pnas.1204480109. Epub 2012 Jul 9.
12. Kurita M1, Okazaki M2, Kaminishi-Tanikawa A1, Niikura M, Takushima A1, Harii K1 (1Dept. Plast. Surg., Kyorin Univ. Sch. Med., 2Dept. Plast. Reconst. Surg., Grad. Sch. Tokyo Med. Dent. Univ.): Differential expression of wound fibrotic factors between facial and trunk dermal fibroblasts. Connect Tissue Res, 53(5):349-354, 2012. Epub 2012 Jul 24.
13. Ishih A, Kawakami C, Todoroki A, Hirai H, Ohori K, Kobayashi F: Outcome of primary lethal and non-lethal Plasmodium yoelii malaria infection in BALB/c and IFN-γ receptor-deficient mice following chloroquine treatment. Parasitol Res, 112(2):773-780, 2013 Feb. doi: 10.1007/s00436-012-3197-y. Epub 2012 Nov 21.
14. Tanabe K, Mita M, Palacpac MNQ, Arisue N, Tougan T, Kawai S, Jombart T, Kobayashi F, Horii T: Within-population genetic diversity of Plasmodium falciparum vaccine candidate antigens reveals geographic distance from a Central sub-Saharan African origin. Vaccine, 31(9):1334-1339, 2013 Feb 18. doi: 10.1016/j.vaccine.2012.12.039. Epub 2013 Jan 4.
15. Niikura M, Inoue S-I, Mineo S, Yamada Y, Kaneko I, Iwanaga S,Yuda M, Kobayashi F: Experimental cerebral malaria is suppressed by disruption of nucleoside transporter 1 but not purine nucleoside phosphorylase. Biochem Biophys Res Commun, 2013 Feb 10. doi:pii: S0006-291X(13)00227-1. 10.1016/j.bbrc.2013.02.004. [Epub ahead of print]
 
【口　演】
1. 高橋　良, 塩原哲夫: Googleカレンダーを利用したFCM機器予約システムの構築：第21回日本サイトメトリー学会学術集会，大阪，平成23年6月25日
2. 高橋　良, 塩原哲夫: Evolving FACS Technology サーバー監視ソフトウェアと温度ロガーを用いたFCM機器モニタリングシステムの開発： 第21回日本サイトメトリー学会学術集会，大阪，平成23年6月25日
3. 井上信一, 新倉　保, 峯尾松一郎, 竹尾　暁, 小林富美惠（シンポジウム）：CD40L発現γδ T細胞を介した樹状細胞活性化によるマラリア原虫感染防御機構. 第23回日本生体防御学会学術総会, 東京, 平成24年7月9-11日.
4. Manabu Higaki, Hiroo Wada, Shin-ichiro Mikura, Tetsuo Yasutake, Masuo Nakamura, Mamoru Niikura, Fumie Kobayashi, Hiroshi Kamma, Shigeru Kamiya, Hajime Takizawa and Hajime Goto (Dep.Resp.Med.): Enhanced neutrophilic inflammation in IL-10 deficient mice exposed to cigarette smoke (via TNF-a regulation). European Respiratory Society in Vienna 2011, Vienna, September 1-5, 2012.
5. 峯尾松一郎, 新倉　保, 井上信一,黒田雅彦, 小林富美惠：妊娠中のマウスマラリア原虫感染による肝機能障害.Liver dysfunction in pregnant mice infected with rodent malaria parasites. 第53回日本熱帯医学会大会, 帯広, 平成24年9月5-6日.
6. Shin-Ichi Inoue, Mamoru Niikura, Satoru Takeo, Shoichiro Mineo, Yasushi Kawakami, Akihiko Uchida, Shigeru Kamiya, Fumie Kobayashi: Enhancement of dendritic cell activation via CD40 ligand-expressing γδ T cells is responsible for protective immunity to Plasmodium berghei XAT.XVIII International Congress for Tropical Medicine and Malaria. Lio de Janeiro, September 23rd-27th, 2012.
7. Shin-Ichi Inoue, Mamoru Niikura, Fumie Kobayashi: Enhancement of dendritic cell activation via CD40 ligand-expressing γδ T cells is responsible for protective immunity to Plasmodium parasites. 第41会日本免疫学会学術集会, 神戸, 平成24年12月5-7日.
8. Ryo Takahashi and Tetsuo Shiohara1　 (1Dept. of Dermatology):　 Increased expression of PILRα on patrolling monocytes sensing HSV is the mechanism by which HSV evades immune attack, The International Investigative Dermatology 2012, Okinawa, Dec 7-8, 2012.
9. Yukiko Ushigome1, Ryo Takahashi, Tetsuo Shiohara1 (1Dept. of Dermatology):Preferential elimination of patrolling monocyte sensing herpesvirus in drug-induced hypersensitivity syndrome, The International Investigative Dermatology 2012, Okinawa, Dec 7-8, 2012.
10. Mamoru Niikura, Shoichiro Mineo, Shin-ichi Inoue, Masahiko Kuroda, Fumie Kobayashi: Development of severe pathology in immunized pregnant mice challenged with lethal malaria parasites. The 6th Nagasaki Symposium on Tropical Emerging Infectious Diseases/The 11th Nagasaki-Singapore Medical Symposium, Nagasaki, December 10th-12th, 2012.
11. 井上信一, 新倉　保, 峯尾松一郎,小林富美惠：γδ T細胞によるマラリア原虫感染防御機構 〜CD40 ligand発現γδT細胞を介した樹状細胞活性化〜　Enhancement of dendritic cell activation via CD40 ligand-expressing γδ T cells is responsible for protective immunity to Plasmodium parasites.　第35回日本分子生物学会年会, 福岡, 平成24年12月11-14日.
12. 檜垣学1、和田裕雄1、新倉保2、安武哲生1、三倉真一郎1、中村益夫1、神谷茂2、菅間 博3、小林富美恵2、滝澤始1、後藤元1（1杏林大学医学部呼吸器内科、2同・感染症学、3同・病因病理学）：タバコが惹起する肺の炎症へのIL-10の抑制的影響,第85回日本生化学会,福岡, 平成24年12月14-16日（発表16日）.
13. Shin-Ichi Inoue, Mamoru Niikura, Shoichiro Mineo, Fumie Kobayashi: γδ T cells exert a bppstomg effect on dendritic cell responses to Plasmodium parasites. Keystone Symposia on Molecular and Cellular Biology, Malaria Meeting, New Orleans, January 20th-25th, 2013（発表22日）.
14. 新倉　保，峯尾　松一郎，井上信一，小林富美惠：妊娠マウスにおけるマラリアの病態重症化の解析．Development of severe pathology in pregnant mice during malaria 第6回寄生虫感染免疫研究会, 大分, 平成25年3月8日-9日（発表8日）.
15. 井上信一, 新倉　保, 峯尾松一郎, 小林富美惠：マラリア原虫感染に対するγδ T細胞サブセットの解明にむけた解析. Characterization of γδ T cell subsets during Plasmodium berghei XAT infection. 第6回寄生虫感染免疫研究会, 大分, 平成25年3月8日-9日（発表8日）.
16. 井上　信一，新倉　保，峯尾　松一郎，川上　泰，内田　明彦，小林　富美惠：マラリア原虫感染防御におけるγδT細胞の機能解析. Functions of γδ T cells in protective immunity against Plasmodium berghei XAT infection. 第82回日本寄生虫学会大会, 東京, 平成25年3月29-31日（発表29日）.
17. Mamoru Niikura, Shin–Ichi Inoue, Shoichirou Mineo, Fumie Kobayashi: Expression of OX40L is enhanced on macrophages through TLR2, TLR4 or TLR9 signaling during attenuated murine malaria parasite infection. 第82回日本寄生虫学会大会, 東京, 平成25年3月29-31日（発表29日）.
18. 金子　明，五十棲　理恵，木村　政継，Chaves Lius Fernando, George Taleo, 竹尾　暁，坪井敬文，田辺和裄，Anders Bjorkman, Marita Troye-Blomberg, Chris Drakeley: マラリア撲滅10年後の三日熱マラリア感染に対する免疫防御．第82回日本寄生虫学会大会, 東京, 平成25年3月29-31日（発表29日）．第82回日本寄生虫学会大会, 東京, 平成25年3月29-31日（発表31日）.