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Faculty of Medicine教員紹介:水川 良子

氏名 水川 良子
ミズカワ ヨシコ MIZUKAWA, Yoshiko
職位教授
所属教室

皮膚科学教室

専攻・専門分野(大学院)

医学専攻 皮膚科学分野(新課程)

内科系専攻 皮膚科学分野(旧課程)

担当科目(学部)皮膚科学
専門分野皮膚免疫アレルギー
研究テーマアレルギー性疾患、薬疹、アトピー性皮膚炎、発汗異常、ウイルス感染症、膠原病、皮膚科一般
略歴1985年 杏林大卒
所有する学位博士(医学)
指導医・専門医・認定医、その他の資格等日本皮膚科学会認定専門医
論文・著書等を含む主要研究業績 Mizukawa Y, Aoyama Y, Takahashi H, Takahashi R, Shiohara T: Risk of Progression to Autoimmune Disease in Severe Drug Eruption: Risk Factors and the Factor-Guided Stratification. J Invest Dermatol 142(3 Pt B): 960-968. e9, 2022.

Mizukawa Y, Kimishima M, Aoyama Y, Shiohara T. Predictive biomarkers for cytomegalovirus reactivation before and after immunosuppressive therapy: A single institution retrospective long-term analysis of patients with drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic symptoms (DRESS). Int J Infect Dis 100: 239-246, 2020.

Mizukawa Y, Sato Y, Ohyama M, Shiohara T. Restoration of sweating disturbance in atopic dermatitis treated with dupilulmab. J Dermatol Sci 100: 79-81, 2020

Mizukawa Y, Yamazaki Y, Shiohara T: Leakage of sweat into the dermo-epidermal junction as a possible trigger for lichen planus lesion development. Arch Dermatol Res 311(1): 71-82, 2019.

Mizukawa Y, Hirahara K, Kano Y, Shiohara T. Drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic syndrome (DRESS) severity score: a useful tool for assessing disease severity and predicting fatal cytomegalovirus disease. J Am Acad Dermatol 80(3): 670-678, 2018.

Sueki H, Mizukawa Y, Aoyama Y. Immune reconstitution inflammatory syndrome in non-HIV immunosuppressed patients. J Dermatol 45: 3-9, 2018.

Narita YM, Horie C, Hirahara K, Kano Y, Shiohara T, Mizukawa Y. Bullous pemphigoid complicated by cytomegalovirus disease as a manifestation of immune reconstitution inflammatory syndrome: retrospective analyses of our institutional cases and literature review. Int J Dermatol 57; 202-208, 2018.

Doi T, Mizukawa Y, Shimoda Y, Shiohara T: Importance of water content of the stratum corneum in mouse models for contact hypersensitivity. J Invest Dermatol 137: 151-158, 2017.

Mizukawa Y, Doi T, Yamazaki Y, Kudo A, Shiohara T: Epidermal neuromedin U attenuates IgE-mediated allergic skin inflammation. PLoS One Jul 27: 11 (7): e0160122, 2016.

Kurata M, Mizukawa Y, Aoyama Y, Shiohara T: Herpes simplex virus reactivation as a trigger of mucous lesions in pemphigus vulgaris. Br J Dermatol 171: 554-560, 2014.

Mizukawa Y, Horie C, Yamazaki Y and Shiohara T: Detection of varicella-zoster virus antigens in lesional skin of zosterifrom lichen planus but not in that of linear lichen planus. Dermatology 225(1); 22-26, 2012.

Mizukawa Y, Shiohara T : Nonpigmenting fixed drug eruption as a possible abortive variant of toxic epidermal necrolysis: immunohistochemical and serum cytokine analyses. Clin Exp Dermatol 35: 493-497, 2010.

Mizukawa Y, Yamazaki Y, Shiohara T: In vivo dynamics of intraepidermal CD8+ T cells and CD4+ T cells during the evolution of fixed drug eruption. Br J Dermatol 158: 1230-1238, 2008.

Mizukawa Y, Yamazaki Y, Teraki Y, Hayakawa J, Hayakawa K, Nuriya H, Kohara M & Shiohara T: Direct evidence for IFN-γ production by effector-memory type intraepidermal T cells residing at an effector site of immunopathology in fixed drug eruption. Am J Pathol 161: 1337-1347, 2002.
所属学会 日本皮膚科学会 (代議員)、日本研究皮膚科学会 (評議員)、日本皮膚免疫アレルギー学会 (代議員)、日本発汗学会 (理事)、日本臨床免疫学会
公的な委員会等の役員・委員歴薬事・食品衛生審議会(副作用・感染等被害判定部会(厚労省))
ひとことメッセージ病態生理をベースにして日常診療に携わっていきます。