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Faculty of Medicine教員紹介:細金 直文

氏名
細金 直文
ホソガネ ナオブミ HOSOGANE, Naobumi
職位教授
所属教室

整形外科学教室

専攻・専門分野(大学院)

医学専攻 整形外科学分野(新課程)

外科系専攻 整形外科学分野(整形外科学)(旧課程)

専門分野脊椎、脊髄
研究テーマ脊椎疾患の臨床的、基礎的研究
略歴1997年 慶應義塾大学医学部卒業
2003年 慶應義塾大学大学院医学研究科博士課程修了
2003年 川崎市立川崎病院 整形外科
2006年-2007年 米国 Hospital for Special Surgery留学
2007年 慶友整形外科
2010年 慶應義塾大学医学部整形外科助教
2013年 防衛医科大学校医学部整形外科助教
2016年 同講師
2018年 杏林大学医学部整形外科准教授
2020年 現職
所有する学位博士(医学)
指導医・専門医・認定医、その他の資格等日本整形外科学会認定整形外科専門医
日本整形外科学会認定脊椎脊髄病医
日本脊椎脊髄病学会認定脊椎脊髄外科指導医
論文・著書等を含む主要研究業績 1.Takeuchi T, Takamizawa Y, Konishi K, Sano H, Takahashi M, Nakamichi K, Kono H, Hosogane N. Evaluation of intraoperative coronal alignment using a computer-assisted rod bending system (CARBS) without intraoperative radiation exposure in adult spinal deformity surgery: a technical note and preliminary results. Spine Deform. 2023 Online ahead of print.
2.Inanaga S, Hasegawa M, Kosuge M, Ichimura S, Morii T, Hosogane N. Relationship between the 25-question Geriatric Locomotive Function Scale and physical function in the elderly people. J Bone Miner Metab. 2023 Online ahead of print.
3.Yagi M, Ames CP, Hosogane N, Smith JS, Shaffrey CI, Schwab FJ, Lafage V, Bess S, Matsumoto M, Watanabe K; International Spine Study Group (ISSG). Comparable satisfaction and clinical outcomes after surgery for adolescent idiopathic scoliosis in the adult (AISA) between the US and Japan. J Orthop Sci. 28(1):92-97, 2023
4.Inoue G, Miyagi M, Saito W, Shirasawa E, Uchida K, Hosogane N, Watanabe K, Katsumi K, Kaito T, Yamashita T, Fujiwara H, Nagamoto Y, Nojiri K, Suzuki S, Okada E, Ueda S, Hikata T, Shiono Y, Watanabe K, Terai H, Tamai K, Matsuoka Y, Suzuki H, Nishimura H, Tagami A, Yamada S, Adachi S, Ohtori S, Furuya T, Orita S, Inage K, Yoshii T, Ushio S, Funao H, Isogai N, Harimaya K, Okada S, Kawaguchi K, Yokoyama N, Oishi H, Doi T, Kiyasu K, Imagama S, Ando K, Kobayashi K, Sakai D, Tanaka M, Kimura A, Inoue H, Nakano A, Ikegami S, Shimizu M, Futatsugi T, Kakutani K, Yurube T, Nakanishi K, Oshima M, Uei H, Aoki Y, Takahata M, Iwata A, Endo H, Seki S, Murakami H, Kato S, Yoshioka K, Hongo M, Abe T, Tsukanishi T, Takaso M, Ishii K. Effect of low body mass index on clinical recovery after fusion surgery for osteoporotic vertebral fracture: A retrospective, multicenter study of 237 cases. Medicine (Baltimore) 101(52):e32330, 2022
5.Hikata T, Takahashi Y, Ishihara S, Shinozaki Y, Nimoniya K, Konomi T, Fujii T, Funao H, Yagi M, Hosogane N, Ishii K, Nakamura M, Matsumoto M, Watanabe K. Risk factors for early reoperation in patients after posterior lumbar interbody fusion surgery. A propensity-matched cohort analysis. J Orthop Sci. S0949-2658(22)00339-6, 2022
6.Yonezawa Y, Guo L, Kakinuma H, Otomo N, Yoshino S, Takeda K, Nakajima M, Shiraki T, Ogura Y, Takahashi Y, Koike Y, Minami S, Uno K, Kawakami N, Ito M, Yonezawa I, Watanabe K, Kaito T, Yanagida H, Taneichi H, Harimaya K, Taniguchi Y, Shigematsu H, Iida T, Demura S, Sugawara R, Fujita N, Yagi M, Okada E, Hosogane N, Kono K, Chiba K, Kotani T, Sakuma T, Akazawa T, Suzuki T, Nishida K, Kakutani K, Tsuji T, Sudo H, Iwata A, Sato T, Inami S, Nakamura M, Matsumoto M, Terao C, Watanabe K, Okamoto H, Ikegawa S. Identification of a Functional Susceptibility Variant for Adolescent Idiopathic Scoliosis that Upregulates Early Growth Response 1 (EGR1)-Mediated UNCX Expression. J Bone Miner Res. 38(1):144-153, 2023
7.Matsuhashi Y, Horiuchi K, Nakagawa T, Takahashi Y, Imabayashi H, Hosogane N, Watanabe K, Matsumoto M, Chiba K. Abrogation of LBX1 in skeletal muscle results in hypoplastic limbs and progressive kyphosis in mice. J Orthop Res. 41(4):884-890, 2023
8.Takeuchi T, Yamagishi K, Konishi K, Sano H, Takahashi M, Ichimura S, Kono H, Hasegawa M, Hosogane N. Radiological Evaluation of Combined Anteroposterior Fusion with Vertebral Body Replacement Using a Minimally Invasive Lateral Approach for Osteoporotic Vertebral Fractures: Verification of Optimal Surgical Procedure. J Clin Med.11(3), 2022
9.Inada N, Ohata T, Maruno H, Morii T, Hosogane N, Ichimura S. Optimal timing for intermittent administration of parathyroid hormone (1-34) for distraction osteogenesis in rabbits. J Orthop Surg Res 17(1):130, 2022
10.Yagi M, Hosogane N, Ames CP, Smith JS, Shaffrey CI, Schwab FJ, Lafage V, Bess S, Suzuki S, Satoshi N, Takahashi Y, Tsuji O, Nagoshi N, Nakamura M, Matsumoto M, Watanabe K; International Spine Study Group (ISSG). Improvement and International Validation of the Predictive Probability of the Patient Demographics, Radiographic Index, and Surgical Invasiveness for Mechanical Failure (PRISM) Model for Preventive Procedures in Adult Spinal Deformity Surgery. Spine (Phila Pa 1976). 47(9):680-690, 2022
11.Otomo N, Lu HF, Koido M, Kou I, Takeda K, Momozawa Y, Kubo M, Kamatani Y, Ogura Y, Takahashi Y, Nakajima M, Minami S, Uno K, Kawakami N, Ito M, Sato T, Watanabe K, Kaito T, Yanagida H, Taneichi H, Harimaya K, Taniguchi Y, Shigematsu H, Iida T, Demura S, Sugawara R, Fujita N, Yagi M, Okada E, Hosogane N, Kono K, Nakamura M, Chiba K, Kotani T, Sakuma T, Akazawa T, Suzuki T, Nishida K, Kakutani K, Tsuji T, Sudo H, Iwata A, Kaneko K, Inami S, Kochi Y, Chang WC, Matsumoto M, Watanabe K, Ikegawa S, Terao C. Polygenic Risk Score of Adolescent Idiopathic Scoliosis for Potential Clinical Use. J Bone Miner Res. 36(8):1481-1491, 2021
12.Isogai N, Yagi M, Nishimura S, Nishida M, Mima Y, Hosogane N, Suzuki S, Fujita N, Okada E, Nagoshi N, Tsuji O, Ishii K, Nakamura M, Matsumoto M, Watanabe K. Risk predictors of perioperative complications for the palliative surgical treatment of spinal metastasis. J Orthop Sci. 26(6):1107-1112 ,2021
13.Yagi M, Michikawa T, Suzuki S, Okada E, Nori S, Tsuji O, Nagoshi N, Asazuma T, Hosogane N, Fujita N, Nakamura M, Matsumoto M, Watanabe K; Keio Spine Research Group. Characterization of Patients with Poor Risk for Clinical Outcomes in Adult Symptomatic Lumbar Deformity Surgery. Spine (Phila Pa 1976). 46(12):813-821, 2021
14.Yagi M, Daimon K, Hosogane N, Okada E, Suzuki S, Tsuji O, Nagoshi N, Fujita N, Nakamura M, Matsumoto M, Watanabe K; Keio Spine Research Group. Predictive Probability of the Global Alignment and Proportion Score for the Development of Mechanical Failure Following Adult Spinal Deformity Surgery in Asian Patients. Spine (Phila Pa 1976). 46(2):E80-E86, 2021
15.M Yagi, N Hosogane, N Fujita, E Okada, S Suzuki, O Tsuji, N Nagoshi, M Nakamura, M Matsumoto, K Watanabe. The patient demographics, radiographic index and surgical invasiveness for mechanical failure (PRISM) model established for adult spinal deformity surgery. Sci Rep.10(1):9341, 2020
16.T Takeuchi, N Hosogane, K Yamagishi, K Satomi, K Matsukawa, S Ichimura. Results of Using a Novel Percutaneous Pedicle Screw Technique for Patients with Diffuse Idiopathic Skeletal Hyperostosis-The Single or Double Endplates Penetrating Screw (SEPS/DEPS) Technique. Spine Surg Relat Res. 4(3):261-268, 2020
17.Hosogane N, Nojiri K, Suzuki S, et al. Surgical Treatment of Osteoporotic Vertebral Fracture with Neurological Deficit-A Nationwide Multicenter Study in Japan. Spine Surg Relat Res. 3(4):361-367, 2019.
18.Kou I, Otomo N, Takeda K, Momozawa Y, Lu HF, Kubo M, Kamatani Y, Ogura Y, Takahashi Y, Nakajima M, Minami S, Uno K, Kawakami N, Ito M, Yonezawa I, Watanabe K, Kaito T, Yanagida H, Taneichi H, Harimaya K, Taniguchi Y, Shigematsu H, Iida T, Demura S, Sugawara R, Fujita N, Yagi M, Okada E, Hosogane N, Kono K, Nakamura M, Chiba K, Kotani T, Sakuma T, Akazawa T, Suzuki T, Nishida K, Kakutani K, Tsuji T, Sudo H, Iwata A, Sato T, Inami S, Matsumoto M, Terao C, Watanabe K, Ikegawa S. Genome-wide association study identifies 14 previously unreported susceptibility loci for adolescent idiopathic scoliosis in Japanese. Nat Commun. 10(1):3685, 2019.
19.Hosogane N, Ames C, Matsumoto M, et al. Ethnic Variations in Radiographic Parameters and SRS-22 Scores in Adult Spinal Deformity: A Comparison Between North American and Japanese Patients Above 50 Years of Age with Minimum 2-Year Follow-up. Clin Spine Surg. 2018. doi: 10.1097/BSD.0000000000000610.
所属学会 日本整形外科学会(代議員)
日本脊椎脊髄病学会(理事)
日本側弯症学会(理事)
アメリカ側弯症学会(Scoliosis Research Society)Member
日本MIST学会(理事)
日本脊椎インストゥルメンテーション学会(理事)
日本腰痛学会(理事)
日本成人脊柱変形学会(幹事)
東日本整形災害外科学会(理事)
関東整形災害外科学会(幹事)
日本脊髄障害医学会(評議員)
日本骨・関節感染症学会(評議員)
公的な委員会等の役員・委員歴先進医療会議技術専門委員(厚生労働省)
健康専門委員(人事院)
学校保健専門委員(脊柱側弯症)(東京都予防医学協会)