研究室・研究グループ紹介：臨床感染症学教室

臨床感染症学教室は、院内の重症・難治性感染症の診療と院内感染対策活動を主として行っております。前者は、コンサルテーション業務を中心に診療を行っています。また、HIV診療は1996年よりエイズ拠点病院として診療をしています。後者は、Infection control team(ICT)あるいはAntimicrobial stewardship team(AST)として、院内感染対策や抗菌薬の適正使用に対する教育や指導を行っており、これらの臨床的な活動から得られる疑問点や問題点についての臨床研究や症例報告を行っています。

近年の主な業績

1. Kurai D, Natori M, Yamada M, Zheng R, Saito Y, Takahashi H. Occurrence and disease burden of respiratory syncytial virus and other respiratory pathogens in adults aged ≥65 years in community: A prospective cohort study in Japan. Influenza Other Respir Viruses. 16(2). 298-307. 2022.
2. Kurai D, Song J, Huang YC, Jie Z, Atanasov P, Jiang X, Hernandez-Pastor L, Huang TH, Park S, Lim K, Richmond PC. Targeted Literature Review of the Burden of Respiratory Syncytial Infection among High-Risk and Elderly Patients in Asia Pacific Region. Infect Dis Ther. 12(3). 807-828. 2023.
3. Kimura H, Kurusu H, Sada M, Kurai D, Murakami K, Kamitani W, Tomita H, Katayama K, Ryo A. Molecular pharmacology of ciclesonide against SARS-CoV-2. J Allergy Clin Immunol. 2020;146:330-331.
4. Ono K, Kishimoto M, Shimasaki T, Uchida H, Kurai D, Deshpande GA, Komagata Y, Kaname S. Reactive arthritis after COVID-19 infection. RMD Open. 6(2). e001350. 2020.
5. Nakamoto K, Saraya T, Ishikawa N, Mikura S, Yoshida Y, Fukukawa N, Taneoka T, Shimasaki T, Kurai D, Ishii H. Efficacy and Safety of Weekly Ultraviolet Germicidal Irradiation for the Reuse of N95 Filtering Respirators. Cureus. 13(9). e18233. 2021.
6. Arikawa S, Fukuoka K, Nakamoto K, Kunitomo R, Matsuno Y, Shimazaki T, Saraya T, Kawakami T, Kishimoto M, Komagata Y, Kurai D, Ishi H, Kaname S. Effectiveness of neutralizing antibody cocktail in hemodialysis patients: a case series of 20 patients treated with or without REGN-COV2. Clin Exp Nephrol. 26(5). 476-485. 2022.
7. Shirai T, Sada M, Saraya T, Kurai D, Sunagawa S, Ishii H, Kimura H. Detailed Analyses of Molecular Interactions between Favipiravir and RNA Viruses In Silico. Viruses. 14(2). 338. 2022.
8. Tokimatsu I, Matsumoto T, Tsukada H, Fujikura Y, Miki M, Morinaga Y, Sato J, Wakamura T, Kiyota H, Tateda K, Yanagisawa H, Sasaki T, Ikeda H, Horikawa H, Takahashi H, Seki M, Mori Y, Takeda H, Kurai D, Hasegawa N, Uwamino Y, Kudo M, Yamamoto M, Nagano Y, Nomura S, Tetsuka T, Hosokai M, Aoki N, Yamamoto Y, Iinuma Y, Mikamo H, Suematsu H, Maruyama T, Kawabata A, Sugaki Y, Nakamura A, Fujikawa Y, Fukumori T, Ukimura A, Kakeya H, Niki M, Yoshida K, Kobashi Y, Tokuyasu H, Yatera K, Ikegami H, Fujita M, Matsumoto T, Yanagihara K, Matsuda J, Hiramatsu K, Shinzato T. Nationwide surveillance of bacterial respiratory pathogens conducted by the surveillance committee of the Japanese Society of Chemotherapy, the Japanese Association for Infectious Diseases, and the Japanese Society for Clinical Microbiology in 2019-2020: General view of the pathogens' antibacterial susceptibility. J Infect Chemother. S1341-321X(23)00099-5. doi: 10.1016/j.jiac.2023.04.008. Online ahead of print. 2023.