大学ホーム医学研究科教育・研究指導教員紹介:

教員紹介:水川 良子


氏名
 
水川 良子
ミズカワ ヨシコ MIZUKAWA, Yoshiko
職位 教授
所属教室
専攻・専門分野
 (大学院)
担当科目(学部) 皮膚科学
専門分野 皮膚免疫アレルギー
研究テーマ アレルギー性疾患、薬疹、アトピー性皮膚炎、発汗異常、ウイルス感染症、膠原病、皮膚科一般
略歴 1985年 杏林大卒
所有する学位 博士(医学)
指導医・専門医・認定医、その他の資格等 日本皮膚科学会認定専門医
論文・著書等を含む主要研究業績 Mizukawa Y, Aoyama Y, Takahashi H, Takahashi R, Shiohara T: Risk of Progression to Autoimmune Disease in Severe Drug Eruption: Risk Factors and the Factor-Guided Stratification. J Invest Dermatol 142(3 Pt B): 960-968. e9, 2022.

Mizukawa Y, Kimishima M, Aoyama Y, Shiohara T. Predictive biomarkers for cytomegalovirus reactivation before and after immunosuppressive therapy: A single institution retrospective long-term analysis of patients with drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic symptoms (DRESS). Int J Infect Dis 100: 239-246, 2020.

Mizukawa Y, Sato Y, Ohyama M, Shiohara T. Restoration of sweating disturbance in atopic dermatitis treated with dupilulmab. J Dermatol Sci 100: 79-81, 2020

Mizukawa Y, Yamazaki Y, Shiohara T: Leakage of sweat into the dermo-epidermal junction as a possible trigger for lichen planus lesion development. Arch Dermatol Res 311(1): 71-82, 2019.

Mizukawa Y, Hirahara K, Kano Y, Shiohara T. Drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic syndrome (DRESS) severity score: a useful tool for assessing disease severity and predicting fatal cytomegalovirus disease. J Am Acad Dermatol 80(3): 670-678, 2018.

Sueki H, Mizukawa Y, Aoyama Y. Immune reconstitution inflammatory syndrome in non-HIV immunosuppressed patients. J Dermatol 45: 3-9, 2018.

Narita YM, Horie C, Hirahara K, Kano Y, Shiohara T, Mizukawa Y. Bullous pemphigoid complicated by cytomegalovirus disease as a manifestation of immune reconstitution inflammatory syndrome: retrospective analyses of our institutional cases and literature review. Int J Dermatol 57; 202-208, 2018.

Doi T, Mizukawa Y, Shimoda Y, Shiohara T: Importance of water content of the stratum corneum in mouse models for contact hypersensitivity. J Invest Dermatol 137: 151-158, 2017.

Mizukawa Y, Doi T, Yamazaki Y, Kudo A, Shiohara T: Epidermal neuromedin U attenuates IgE-mediated allergic skin inflammation. PLoS One Jul 27: 11 (7): e0160122, 2016.

Kurata M, Mizukawa Y, Aoyama Y, Shiohara T: Herpes simplex virus reactivation as a trigger of mucous lesions in pemphigus vulgaris. Br J Dermatol 171: 554-560, 2014.

Mizukawa Y, Horie C, Yamazaki Y and Shiohara T: Detection of varicella-zoster virus antigens in lesional skin of zosterifrom lichen planus but not in that of linear lichen planus. Dermatology 225(1); 22-26, 2012.

Mizukawa Y, Shiohara T : Nonpigmenting fixed drug eruption as a possible abortive variant of toxic epidermal necrolysis: immunohistochemical and serum cytokine analyses. Clin Exp Dermatol 35: 493-497, 2010.

Mizukawa Y, Yamazaki Y, Shiohara T: In vivo dynamics of intraepidermal CD8+ T cells and CD4+ T cells during the evolution of fixed drug eruption. Br J Dermatol 158: 1230-1238, 2008.

Mizukawa Y, Yamazaki Y, Teraki Y, Hayakawa J, Hayakawa K, Nuriya H, Kohara M & Shiohara T: Direct evidence for IFN-γ production by effector-memory type intraepidermal T cells residing at an effector site of immunopathology in fixed drug eruption. Am J Pathol 161: 1337-1347, 2002.
所属学会 日本皮膚科学会 (代議員)、日本研究皮膚科学会 (評議員)、日本皮膚免疫アレルギー学会 (代議員)、日本発汗学会 (理事)、日本臨床免疫学会
公的な委員会等の役員・委員歴 薬事・食品衛生審議会(副作用・感染等被害判定部会(厚労省))
ひとことメッセージ 病態生理をベースにして日常診療に携わっていきます。
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