大学ホーム医学研究科教育・研究指導教員紹介：

教員紹介：徳嶺　譲芳


氏名
 		 徳嶺　譲芳
トクミネ　ジョウホウ TOKUMINE, Joho
職位 教授
学内の役職・委員等 CVC委員
所属教室

麻酔科学教室

専攻・専門分野
　（大学院）

医学専攻 麻酔科学分野（新課程）
外科系専攻 麻酔科学分野（旧課程）

担当科目（学部） 麻酔科学
担当科目（大学院） 「血管確保」
専門分野 麻酔科学
研究テーマ 安全な中心静脈穿刺手技と教育体制の構築
気道エコー
略歴 1988年　琉球大学大学院 医学研究科 入学
1992年　同上　修了
2000年　カリフォルニア大学サンディエゴ校 留学
2002年　同上　帰国
2009年　日本臨床麻酔学会誌賞 受賞
2013年　日本麻酔学会第59回学術集会 最優秀演題賞 受賞
所有する学位 博士（医学）
指導医・専門医・認定医、その他の資格等 麻酔指導医
麻酔科標榜医
論文・著書等を含む主要研究業績 1. Tokumine J, Moriyama K, Yorozu T. Clues for diagnosing misplaced central venous catheter in the right ascending lumbar vein during right femoral venous access. World J Clin Cases. 2024 (in press).
2. Takeuchi N, Koshihara M, Motoyasu A, Tokumine J, Nakazawa H, Ozaki M, Yorozu T. General anesthesia for cesarean section in a pregnant woman with systemic vascular malformation: a case report. JA Clin Rep. 2023;9(1):88.
3. Nakazawa H, Uzawa K, Tokumine J, Lefor AK, Motoyasu A, Yorozu T. Airway ultrasound for patients anticipated to have a difficult airway: Perspective for personalized medicine. World J Clin Cases. 2023;11(9):1951-1962.
4. Tokumine J, Nakazawa H, Morimoto Y, Yorozu T. Do not misidentify a venous valve as a venous dissection. Radiol Case Rep. 2023;18(4):1403-1405.
5. Kohyama T, Fujimaki K, Sasamori H, Tokumine J, Moriyama K, Yorozu T. Inadvertent catheter misplacement into the subclavian artery during ultrasound-guided internal jugular venous catheterization: a case report. JA Clin Rep. 2023;9(1):58.
6. Sekiguchi S, Moriyama K, Tokumine J, Lefor AK, Nakazawa H, Tomita Y, Yorozu T. Near-infrared venous imaging may be more useful than ultrasound guidance for novices to obtain difficult peripheral venous access: A crossover simulation study. Medicine (Baltimore). 2023;102(12):e33320.
7. Wada N, Furutani A, Tokumine J, Nakazawa H, Shimazu K, Yorozu T. Ultrasound-Guided Glossopharyngeal Nerve Block for an Awake Intubation in a Patient Predicted to Have a Difficult Airway: A Case Report. A A Pract. 2023;17(5):e01682.
8. Moriyama K, Koh M, Takeuchi N, Tokumine J, Yorozu T Aberrant cessation of inhalation anesthesia in an anesthesia machine equipped with a digital vaporizer. Can J Anaesth. 2023.
9. Harumasa Nakazawa, Joho Tokumine, Alan Lefor, Katsuya Yamamoto, Hiroyuki Karasawa, Keisuke Shimazu, Tomoko Yorozu. Use of a photoacoustic needle improves needle tip recognition in a video recording of simulated ultrasound-guided vascular access: a pilot study. J Vasc Access, 2022:11297298221122137.
10. Sugiki D, Matsushima H, Asao T, Tokumine J, Lefor AK, Kamisasanuki T, Suzuki M, Gomei S. A web-based self-learning system for ultrasound-guided vascular access. Medicine 2022;101:43(e31292).
11. Moriyama K, Ando T, Kotani M, Tokumine J, Nakazawa H, Motoyasu A, Yorozu T. Risk factors associated with increased incidences of catheter-related bloodstream infection. Medicine 101(42): e31160, 2022. doi: 10.1097/MD.0000000000031160.
12. Sawada R, Watanabe K, Tokumine J, Lefor AK, Ando T, Yorozu T. Ultrasound-guided rectus sheath block for anterior cutaneous nerve entrapment syndrome after laparoscopic surgery: A case report. World J Clin Cases. 2022;10(7):2357-2362. doi: 10.12998/wjcc.v10.i7.2357.
13. Noguchi H, Seki H, Tokumine J, Nakazawa H, Yorozu T. Bleeding After Central Venous Catheter Placement in a Patient With Undiagnosed Acquired Hemophilia A: A Case Report. Cureus. 2022;14(7):e27444. doi: 10.7759/cureus.27444.
14. Nagase M, Nagase T, Tokumine J, Saito K, Sunami E, Shiokawa Y, Matsumura G. Formalin-free soft embalming of human cadavers using N-vinyl-2-pyrrolidone: perspectives for cadaver surgical training and medical device development. Anat Sci Int. 2022. doi: 10.1007/s12565-022-00664-9.
15. Kikuchi M, Asao T, Tokumine J, Lefor AK, Matsushima H, Andoh H, Tanaka K, Kanamoto M, Ideno Y. A novel system for teaching the in-plane vascular access technique: A simulation study. Medicine (Baltimore). 2021;100(37):e27201.
16. Okano H, Mayumi T, Kataoka Y, Banno M, Tsujimoto Y, Shiroshita A, Taito S, Tokumine J. Outcomes of Simulation-Based Education for Vascular Access: A Systematic Review and Meta-Analysis. Cureus 2021;13(8):e17188.
17. Watanabe K, Tokumine J, Lefor AK, Nakazawa H, Yamamoto K, Karasawa H, Nagase M, Yorozu T. Photoacoustic needle improves needle tip visibility during deep peripheral nerve block. Sci Rep. 2021;11(1):8432.
18. Tokumine J, Watanabe H, Moriyama K, Tabuchi S, Motoyasu A, Kageyama E, Yorozu T. In Response: " Massive leak in CO2 absorber of Perseus A500 did not inhibit mechanical ventilation but manual bag ventilation: A case report with experimental reproduction." A A Pract. 2021;15(7):e01498.
19. Watanabe H, Moriyama K, Tokumine J, Tabuchi S, Motoyasu A, Kageyama E, Yorozu T. Massive leak in CO2 absorber of Perseus A500 did not inhibit mechanical ventilation but manual bag ventilation: A case report with experimental reproduction. A A Pract. 2021;15(3):e01425.
20. Tsuji D, Okano H, Tokumine J, Lefor AK, Ema S, Yorozu T. Midline catheter placement in an obese patient with difficult venous access. Med Case Rep Study Protoc. 2020;1:1(e0009).
21. Watanabe K, Tokumine J, Lefor AK, Yorozu T. Shallow-angle needle guide for ultrasound-guided internal jugular venous catheterization: A randomized controlled crossover simulation study (CONSORT). PLoS One. 2020 Jun 30;15(6):e0235519.
22. Katayama A, Watanabe K, Tokumine J, Lefor AK, Nakazawa H, Jimbo I, Yorozu T. Cricothyroidotomy needle length is associated with posterior tracheal wall injury: A randomized crossover simulation study (CONSORT). Medicine (Baltimore). 2020 Feb;99(9):e19331.
23. Watanabe K, Tokumine J, Lefor AK, Moriyama K, Yorozu T. Ultrasound-guided hydrodissection of an entrapped saphenous nerve after lower extremity varicose vein stripping: A case report. A A Pract. 2019 Nov 19. doi: 10.1213/XAA.0000000000001143.
24. Safety Committee of Japanese Society of Anesthesiologists. Practical guide for safe central venous catheterization and management 2017. [Working Group for Safe Central Venous Catheterization and Management: Nishiwaki K, Kawamoto M, Shibata Y, Takeuchi M, Tanaka K, and Tokumine J], J Anesth. 2019 Nov 30. doi: 10.1007/s00540-019-02702-9. [Epub ahead of print] Review.
25. Jimbo I, Uzawa K, Tokumine J, Mitsuda S, Watanabe K, Yorozu T. Ultrasonographic identification of the cricothyroid membrane in a patient with a difficult airway as a result of cervical hematoma caused by hemophilia: a case report. BMC Anesthesiol. 2019 Jul;19(1):124.
26. Asao T, Kikuchi M, Tokumine J, Matsushima H, Andoh H, Tanaka K, Kanamoto M, Ideno Y. Optical skill-assist device for ultrasound-guided vascular access: A preliminary simulation study. Medicine (Baltimore). 2019 Jun;98(26):e16126.
27. Watanabe K, Moriyama K, Tokumine J, Yorozu T. Effect of hangebyakujutsutemmato on pregabalin-induced dizziness in a rat model of neuropathic pain, Traditional & Kampo Medicine, 10 May 2019. https://doi.org/10.1002/tkm2.1218
28. Saijo F, Mutoh M, Tokumine J, Yoshinobu O, Hama H, Namima T, Shibahara M, Tokumura H: Late fracture of Groshong ports: A report of the three cases. J Vasc Access. 129729819834512, 2019.
29. Katayama A, Nakazawa H, Tokumine J, Lefor AK, Watanabe K, Asao T, Yorozu T: A high-fidelity simulator for needle cricothyroidotomy training is not associated with increased proficiency compared with conventional simulators: A randomized controlled study. Medicine (Baltimore). 98(8):e14665, 2019.
30. Mitsuda S, Tokumine J, Matsuda R, Yorozu T, Asao T: PICC insertion in the sitting position for a patient with congestive heart failure: A case report. Medicine (Baltimore). 98(6):e14413, 2019.
31. Yokota T, Tokumine J, Lefor AK, Hasegawa A, Yorozu T, Asao T: Ultrasound-guided placement of a midline catheter in a patient with extensive postburn contractures: A Case report. Medicine (Baltimore). 98(3):e14208, 2019.
32. Wada N, Tashima K, Motoyasu A, Nakazawa H, Tokumine J, Chinzei M, Yorozu T: Anesthesia for patient with anti-N-methyl-D-aspartate receptor encephalitis: A case report with a brief review of the literature. Medicine (Baltimore). 97(50):e13651,2018.
33. Watanabe K, Tokumine J, Lefor AK1, Motoyasu A, Moriyama K, Yorozu T (1Jichi Medical University): A Shallow Angle Short-Axis Out-of-Plane Approach Reduces the Rate of Posterior Wall Injuries in Central Venous Catheterization: A Simulation Study. Biomed Res Int. eCollection 2018:4793174, 2018.
34. Okano H, Uzawa K, Watanabe K, Motoyasu A, Tokumine J, Lefor AK, Yorozu T : Ultrasound-guided identification of the cricothyroid membrane in a patient with a difficult airway: a case report. BMC Emerg Med. 18(1):5, 2018.
35. Mitsuda S, Motoyasu A, Tokumine J, Watanabe K, Morimoto Y, Yorozu T: Atypical Venous Valve of the Internal Jugular Vein. J Cardiothorac Vasc Anesth. 32(1):e30-e31, 2018.
36. Watanabe K, Mitsuda S, Motoyasu A, Tokumine J, Moriyama K, Yorozu T. Iatrogenic carpal tunnel syndrome induced by wrist extension for placement of an indwelling radial artery catheter: a case report. JA Clin Rep. 3(1):51, 2017.
37. Watanabe K, Tokumine J, Lefor AK, Moriyama K, Sakamoto H, Inoue T, Yorozu T: Postoperative analgesia comparing levobupivacaine and ropivacaine for brachial plexus block: A randomized prospective trial. Medicine (Baltimore). 2017;96(12):e6457.
38. Watanabe K, Tokumine J, Yorozu T, Moriyama K, Sakamoto H, Inoue T. Particulate-steroid betamethasone added to ropivacaine in interscalene brachial plexus block for arthroscopic rotator cuff repair improves postoperative analgesia. BMC Anesthesiol. 2016;16(1):84.
39. Watanabe K, Mitsuda S, Tokumine J, Lefor AK, Moriyama K, Yorozu T. Quadratus lumborum block for femoral-femoral bypass graft placement: A case report. Medicine (Baltimore). 2016;95(35):e4437.
40. Uzawa K, Tokumine J, Lefor AK, Takagi T, Watanabe K, Yorozu T: Difficult Airway Due to an Undiagnosed Subglottic Tumor: A Case Report. Medicine (Baltimore). 2016;95(15):e3383.
41. Kawagishi K, Tokumine J, Lefor AK: The relationship of the subclavius muscle with relevance to venous cannulation below the clavicle. Anesthesiol Res Pract. 2016:6249483,2016.
42. Hirai E, Tokumine J, Lefor AK, Ogura S, Kawamata M: Bladder explosion during transurethral resection of the prostate with nitrous oxide inhalation. Case Rep Anesthesiol. 2015:464562,2015.
43. Morimoto Y, Shimamoto Y, Tanaka E, Tokumine J: Images in Anesthesiology: Detection of large inferior thyroid Artery by ultrasound prescan before internal jugular vein catheterization. Anesthesiology 123(4):927,2015.
44. Tokumine J, Matsushima H, Lefor AK, Igarashi H, Ono K: Ultrasound-guided subclavian venipuncture is more rapidly learned than the anatomic landmark technique in simulation training. J Vasc Access.16(2):144-147,2015.
45. Morimoto Y, Tanaka E, Shimamoto Y, Tokumine J: Dissection of the posterior wall by guide-wire during internal jugular vein catheterization. J Anesth 29(2):289-291,2015.
46. Tokumine J, Lefor AK, Yasutani T, Sekiguchi T, Motoyasu A, Yorozu T: Abduction of the ipsilateral upper arm straightens the axillary vein. Int Arch Clin Anesth Res 1:23-24,2015.
47. Tadokoro T, Tokumine J, Lefor AT, Kawabata T, Yoza K, Kinjo T. The three-step method for ultrasound-guided pediatric internal jugular venous catheterization: a clinical trial. J Anesth. 2015;29(1):131-3.
48. Tokumine J, Lefor AT, Yonei A, Kagaya A, Iwasaki K, Fukuda Y: Three-step method for ultrasound-guided central vein catheterization. Br J Anaesth. 110:368-73,2013.
49. Tomoyose T, Ohama M, Yamanoha A, Masuzaki H, Okudaira T, Tokumine J: Real-time ultrasound-guided central venous catheterization reduces the need for prophylactic platelet transfusion in thrombocytopenic patients with hematological malignancy. Transfus Apher Sci. 49:367-9,2013.
50. Tokumine J, Lefor AT, Morimoto Y, Sanuki M, Asai T, Ohde S: A novel cannula-over-needle system for ultrasound-guided central venous catheterization. J Anesth.26:941-2,2012.
51. Tokumine J, Sugahara K, Nitta K, Fuchigami T, Abe M, Gushiken K, Oda M, Okayama H: Aberrant halt of syringe pump motion: an improved system to prevent false setting of the syringe. J Anesth. 20:118-21,2006.
52. Tokumine J, Sugahara K, Gushiken K, Ohta M, Matsuyama T, Saikawa S: Non-zero basal oxygen flow a hazard to anesthesia breathing circuit leak test. Anesth Analg. 100:1056-8,2005.
53. Kinjo S, Tokumine J, Sugahara K, Kakinohana M, Iha K, Matsuda H, Akasaki M, Yamashiro S: Unexpected hemodynamic deterioration and mitral regurgitation due to a tissue stabilizer during left anterior descending coronary anastomosis in off-pump coronary artery bypass graft surgery. Ann Thorac Cardiovasc Surg. 11:324-8,2005.
54. Tokumine J, Sugahara K, Fuchigami T, Teruya K, Nitta K, Satou K: Unanticipated full stomach at anesthesia induction in a type I diabetic patient with asymptomatic gastroparesis. J Anesth. 19:247-8, 2005.
55. Tokumine J, Sugahara K, Matsuyama T, Nitta K, Fuchigami T, Miyaguni T: Shaw scalpel for breast mastectomy in a pacemaker-implanted patient. J Anesth. 19:349, 2005.
56. Koja H, Tokumine J, Sugahara K, Yamashiro S, Uezu T, Koja K: Subcutaneous pulsating neck mass after left internal jugular venipuncture. J Cardiothorac Vasc Anesth. 18:806-8,2004.
57. Kawabata T, Tokumine J, Nakamura S, Sugahara K: Unanticipated vomiting and pulmonary aspiration at anesthesia induction in a formula-fed 4-month-old infant.
Anesthesiology. 100:1330-1,2004.
58. Kakinohana M, Tokumine J, Kawashima S, Koja H, Sugahara K: Patient-controlled sedation using propofol in eight patients with endstage renal failure. J Anesth. 18:39-42,2004.
59. Tokumine J, Sugahara K, Ura M, Takara I, Oshiro M, Owa T: Lingual tonsil hypertrophy with difficult airway and uncontrollable bleeding. Anaesthesia. 58:390-1,2003.
60. Tokumine J, Kakinohana O, Cizkova D, Smith DW, Marsala M: Changes in spinal GDNF, BDNF, and NT-3 expression after transient spinal cord ischemia in the rat. J Neurosci Res. 74:552-61,2003.
61. Tokumine J, Sugahara K, Tomori T, Nagasawa Y, Takaesu Y, Hokama: A. Tissue necrosis caused by extravasated propofol. J Anesth. 16:358-9,2002.
62. Tokumine J, Iha H, Okuda Y, Shimabukuro T, Shimabukuro T, Ishigaki K, Nakamura S, Takara I: Appropriate method of administration of propofol, fentanyl, and ketamine for patient-controlled sedation and analgesia during extracorporeal shock-wave lithotripsy. J Anesth. 14:68-72,2000.
63. Tokumine J, Iha H, Okuda Y, Ishigaki K, Oshiro M, Nakamura S, Fuchibe M, Teruya K: Gastric tube guide-equipped laryngeal mask airway. J Anesth. 14:221-3,2000.
64. Tokumine J, Iha H, Okuda Y, Nitta K, Ishigaki K, Oshiro M, Shimabukuro T: A comparison between low-flow leak test and oxygen flush leak test. J Anesth. 14:191-3, 2000.
所属学会 日本麻酔科学会
日本臨床麻酔学会（学会誌査読委員）
日本医学シミュレーション学会（理事）
医療の質・安全学会(代議員）
公的な委員会等の役員・委員歴 一般社団法人 医療安全全国共同行動「行動目標3b」中心静脈穿刺 支援部会委員長
公益社団法人 日本麻酔科学会 中心静脈カテーテル挿入の手引き改訂ワーキング・グループ委員
学外活動Medicine (Baltimore) Academic Editor
BioMed Research International, Academic Editor
The Journal of International Medical Research, Editorial Board Member
Current Cardiology Review, Executive Guest Editor
学生のみなさんへ 多様化した社会で生きる
現在の社会は昔のような成功モデルがありません。ですから、皆さんはどのように生きるかを考えることから始めなければなりません。それは悩ましいことかもしれません。しかし、昔を生きた私から見ると、現代の若者はとても自由で羨ましい。人は社会的な生き物です。自分の自由だけを主張するのではなく、他人の自由を尊重することで、初めて自分自身も自由でいられます。医療の世界は、緊張と危険を強いる職場です。その中で、自由におおらかに、そして他人と協力して生きる術を身につけてください。
関連サイト エコーガイド下中心静脈穿刺
電子メール jtokumine@ks.kyorin-u.ac.jp
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